Interleukin-18/interleukin-10 ratio in predicting the further course of chronic obstructive pulmonary disease combined with hypertension

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Date

2019

Authors

Kapustnik, Valeriy
Kostyuk, Inna
Melenevych, Anastasiia

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Abstract

The article presents the results of analysis of main prognostically signifcant criteria depending on the values of interleukin-18/interleukin-10 (IL-18/IL-10) ratio in patients with chronic obstructive pulmonary disease (COPD) combined with hypertension (HT). Growth of IL-18/IL-10 ratio was associated with emphysematous changes in chest X-ray, increase in the degree of dyspnea, decreased exercise tolerance, increased levels of desaturation, lower body mass index, waist and mid-arm circumferences. The results of echocardiography revealed that all patients with comorbid pathology had signs of myocardial overload.

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Keywords

COPD, hypertension, interleukin-18, interleukin-10

Citation

Kapustnyk V. A. Interleukin-18/interleukin-10 ratio in predicting the further course of chronic obstructive pulmonary disease combined with hypertension / V. A. Kapustnyk, I. F. Kostyuk, A. Ya. Melenevych // General medicine. – 2019. – Т. 21, № 1. – С. 3–6.