The role of plasminogen activator ingibitor type 1 in the development of endothelial disfunction in patients with acute myocardial infarction and type 2 diabetes mellitus
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The high risk of vascular accidents is an incentive to study the pathogenetic mechanisms of thrombotic
formation in type 2 diabetes. Plasminogen activator inhibitor type 1, which is a member of the superfamily
of serine protease inhibitors and the main inhibitor of fibrinolysis in the plasminogen activator system, plays
a key role in the pathogenesis of arterial and venous thrombosis and, therefore, contributes to the occurrence
of thrombotic events.
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The role of plasminogen activator ingibitor type 1 in the development of endothelial disfunction in patients with acute myocardial infarction and type 2 diabetes mellitus / D. V. Minukhina, V. D. Babadzhan, P. G. Kravchun, I. P. Dunaeva, D. V. Minukhin, A. G. Krasnoyaruzhskiy, D. A. Yevtushenko // Проблеми ендокринної патології. – 2019. – № 1 (67). – С. 30–37.