The role of plasminogen activator ingibitor type 1 in the development of endothelial disfunction in patients with acute myocardial infarction and type 2 diabetes mellitus
Date
2019
Authors
Кравчун, Павло Григорович
Бабаджан, Володимир Данилович
Мінухіна, Діана Валеріївна
Дунаєва, Інна Павлівна
Мінухін, Д.В.
Краснояружський, Андрій Григорович
Євтушенко, Д.О.
Minukhina, Diana
Babadzhan, Volodymyr
Kravchun, Pavlo H.
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Abstract
The high risk of vascular accidents is an incentive to study the pathogenetic mechanisms of thrombotic
formation in type 2 diabetes. Plasminogen activator inhibitor type 1, which is a member of the superfamily
of serine protease inhibitors and the main inhibitor of fibrinolysis in the plasminogen activator system, plays
a key role in the pathogenesis of arterial and venous thrombosis and, therefore, contributes to the occurrence
of thrombotic events.
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Citation
The role of plasminogen activator ingibitor type 1 in the development of endothelial disfunction in patients with acute myocardial infarction and type 2 diabetes mellitus / D. V. Minukhina, V. D. Babadzhan, P. G. Kravchun, I. P. Dunaeva, D. V. Minukhin, A. G. Krasnoyaruzhskiy, D. A. Yevtushenko // Проблеми ендокринної патології. – 2019. – № 1 (67). – С. 30–37.