Correction of cytokine misbalance in patients with chronic generalized periodontitis of initial-I degrees of severity by means of local application of quercetinum granules and liposomal quercetinum-lecithin complex.

Abstract

The research in question demonstrates lipoflavon capability to normalize misbalance of cytokines in periodontal tissues, thus retarding process of inflammation and destruction of tissues and improving reparation of periodontal structures. High therapeutic efficiency of the liposomal quercetin-lecithin complex for patients with chronic generalized periodontitis, especially that of initial-I degrees of severity was shown to be determined by anti-inflammatory, immunomodulating and periodontoprotecting effects. This allows to recommend lipoflavon for local application as pathogenetically substantiated drug in treatment of generalized periodontitis.