Proinflammatory cytokines Il-8 and TNFα with Henoch-Schonlein purpura in children

Abstract

Henoch-Schonlein purpura (HSP) belongs to a group of systemic vasculitis with predominant damage to small caliber vessels (EULAR/Pres, 2006). Difficulties in diagnosis in the early stages and the likelihood of developing complications leaves HSP in the top of the current issues of pediatrics today. Kidney damage is observed in 20-50% of patients with HSP and leads to complications In recent years, the question of prognostic markers of progression of HSP remains open.