Serum chemerin and renal dysfunction in hypertensive patients with obesity
Date
2018-09-26
Authors
Ivanchenko, Svitlana
Honchar, Oleksii
Kovalyova, Olga
Journal Title
Journal ISSN
Volume Title
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Abstract
It is known that the presence of micromacroalbuminuria
is a reliable marker of kidney damage
in patients with essential hypertension (EH). The presence
of protein in the urine of patients with EH is a predictor of
kidney disease progression and an independent factor of
cardiovascular risk. Currently, there are few biomarkers
that are used for diagnosis and monitoring of renal function.
Recently, a novel adipocytokine, chemerin, is being
widely studied. Analysis of chemerin role in the inflammatory
process suggess its possible role in the development
of kidney tissue inflammation and renal dysfunction in cardiovascular
disease.The aim of our study was to examine
the relationship between levels of serum chemerin, glomerular
filtration rate (GFR) and the presence of proteinuria
in patients with essential hypertension with different
body mass index (BMI).
Description
Keywords
essential hypertension, chemerin, renal dysfunction
Citation
Ivanchenko S. V. Serum chemerin and renal dysfunction in hypertensive patients with obesity / S. V. Ivanchenko, O. M. Kovalyova, O. V. Honchar // Український кардіологічний журнал. – 2018. – Додаток 1 : ХІХ Національний конгрес кардіологів України : тези доповідей, Київ, 26–28 вересня 2018. – С. 39–40.