Correction of cytokine misbalance between pro-inflammatory TNF-α and anti-inflammatory IL-4 in patients with chronic generalized periodontitis

Abstract

The cytokine level of the patients with initial and I degrees of severity in the basic group after six-month treatment was TNF-α - 27,51 ± 2,57 pg/ml, which was 107 % higher than in the C groups and anti-inflammatory ІL-4 - 292,2 ± 20,77 pg/ml, which was 19 % lower than in the C groups. The cytokine level of the patients in the comparison group after six-month treatment was TNF-α - 32,72 ± 3,56 pg/ml, which was 109 % higher than in the C groups and anti-inflammatory ІL-4 - 261,7 ± 16,25 pg/ml, that was 17 % lower than in the C groups.