The effect of light with different wavelengths and different photosensitizers on the effectiveness of antimicrobial photodynamic therapy on cultures of E. COLI AND CANDIDA ALBICANS (IN VITRO)

Abstract

The use of PDT (photodynamic therapy) is a promising approach for treating microbial dysbiosis in the oral cavity. Theindepend ent effect of light radiation or treatment with photosensitizers (dimegine and photoditazine) does not inhibit the growth of E. coli and Candida albicans cultures. PDT (green, blue, and violet light) with dimegine and photoditazine inhibits E. coli colony growth; the best outcome occurs with a 5-minute exposure to violet light. When using PDT (red, green, blue, and violet light) with methylene blue, E. coli colony growth is absent. Inhibition of Candida albicans colony growth occurred under red,g reen, blue, and violet light with photosensitizers in the following order of effectiveness: dimegine, photoditazine, methylene blue. This inhibition is proportional to the exposure time.