Dependence of anthropometric and hemodynamic parameters on the interleukin-22 level in patients with arterial hypertension

Abstract

Arterial hypertension (AH) is one of the most pressing medical and social issues of the modern world. Literature data indicate a relationship between AH and inflammatory process, which is exacerbated by the presence of overweight. Recently, the role of cytokines in the pathogenesis of AH and metabolic disorders has been actively studied. In 2000, a group of researchers discovered a new interleukin-22 (IL-22) molecule, a pro-inflammatory cytokine, which showed a pro-hypertensive effect in a mouse model. However, data on the involvement of IL-22 in the pathogenesis of obesity and hypertension in humans are contradictory and require further study. The aim of our study was to study anthropometric and hemodynamic parameters in patients with AH, depending on the level of interleukin-22.