Morphological justification of the salivary gland tissue resection boundaries during surgical treatment of patients with pleomorphic adenomas
Date
2021-09
Authors
Brodetskyi, Igor
Malanchuk, Vladislav
Dyadyk, Olena
Kulbashna, Yaroslava
Astapenko, Olena
Kapustnyk, Nataliia
Myroshnychenko, Mykhailo
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
The aim is to substantiate morphologically the resection boundaries of the salivary gland tissue in the surgical treatment of patients with pleomorphic adenoma of different histological variants. These changes were: violation of the ratio of the specific volumes of the parenchyma and stroma; atrophy of the terminal sections and ducts with cystic expansion of some ducts; thickening of the secretion and formation of calculi in the lumen of some ducts; atrophic and alterative changes in the epithelial lining the terminal sections and ducts; sclerosis and lipomatosis, areas with hyalinosis and dystrophic calcification in the stroma; hemodynamic disturbances in the stroma with a decrease in the number of vessels; pronounced focal or diffuse immune infiltration in the stroma in some areas with the lymphoid follicles formation.The comprehensive study has confirmed that removal of the tumor with the adjacent tissue of the salivary gland at a distance of 1.0 cm in patients with pleomorphic adenoma of various histological variants is the most justified from the morphological point of view.
Description
Keywords
salivary gland, morphology, pleomorphic adenoma, resection boundaries
Citation
Morphological justification of the salivary gland tissue resection boundaries during surgical treatment of patients with pleomorphic adenomas / I. S. Brodetskyi, V. A. Malanchuk, O. O. Dyadyk, Y. A. Kulbashna, O. O. Astapenko, N. V. Kapustnyk, M. S. Myroshnychenko // Wiadomosci Lekarskie. – 2021. – Volume LXXIV, issue 9. – Р. 2182–2186.