The influence of tumor necrosis factor-α on processes of citolisis and cholestasis in patients with comorbid pathology

Abstract

Tumor necrosis factor-α (TNF-α) is an adipokine that can cause the cytotoxic effects and can stimulate the apoptosis, impairing liver function. There is a need in further study of TNF-α influence on liver cells properties and its role in the pathogenesis of nonalcoholic fatty liver disease against the background of diabetes mellitus type 2 and obesity.

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Keywords

tumor necrosis factor-α, nonalcoholic fatty liver disease, diabetes mellitus type 2, obesity

Citation

Ogneva O. V. The influence of tumor necrosis factor-α on processes of cytolysis and cholestasis in patients with comorbid patholoy» / O. V. Ogneva // 6th International Scientific Interdisciplinary Conference (ISIC) for medical students and young doctors, Kharkiv, 16–17 May 2013 : Abstract book / KhNMU. – Kharkiv, 2013. – Р. 77–78.

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