Malondialdehyde and superoxide dismutase as predictive biomarkers of periodontitis in oral fluid

Abstract

A comparative analysis of the efficacy of the complex treatment in two groups of patients showed that all the drugs resulted in a significant increase of the malonic dialdehyde values after 1 month treatment. In the BG, MDA amounted to 4,73 ± 0,57 µmol/l (P < 0,05), and with the use of gel with QG amounted to 4,95 ± 0,51 µmol/l (P < 0,05). After 6 months, the MDA increased to 4,81 ± 0,25 µmol/l and 4,86 ± 0,43 µmol/l (P > 0,05), and after 1 year to 4,78 ± 0,33 µmol/l and 4,91 ± 0,55 µmol/l, respectively (P > 0,05). Within 1 month, the SOD for stage initial-I degrees of severity CGP increased to 6,35 ± 0,18 c.u. (P < 0,001) with LQLC and to 5,81 ± 0,21 c.u. (P < 0,001) with the use of QG (P > 0,05). In case of stage initial-I CGP, the superoxide dismutase decrease up to 5,51 ± 0,18 c.u. (LQLC) and 5,27 ± 0,11 (QG) was registered after 6 months (P > 0,05), and after 1 year - 5,42 ± 0,13 and 5,02 ± 0,13 c.u. accordingly (P > 0,05).