Therapeutic possibilities of spironolactone in remodeling of the left ventricule of myocardium in patients with arterial hypertension and chronic obstructive pulmonary disease

Abstract

The objective: to study the effect of spironolactone on left ventricule (LV) geometry in patients with arterial hypertension(AH) in combination with chronic obstructive pulmonary disease (COPD) with II degree of airway obstruction. Conclusions. Additional use of spironolactone to the basic treatment of heart failure provides decrease of concentric LV hypertrophy and reappearance of normal LV geometry in patients with AH and COPD, that agrees with the data of other researchers.