Experimental research of allergenic effect of coformulated antihypertensive drug
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Date
2016-04-07
Authors
Молотягін, Дмитро Геннадійович
Molotyahin, Dmytro
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Abstract
The aim of the research is to study the allergenic effect of a new coformulated antihypertensive COMBI drug that contains bisoprolol, lisinopril and indapamide. Therefore, COMBI drug in the fixed doses along with overlapping sensitization with integral indicators, intradermal samples, diagnostic tests (reaction of specific agglomeration of leukocytes, the reaction of alteration of neutrophils), number of blood eosinophils has no allergenic effect. The absence of specific sensitization isconfirmed with the negative conjunctival sample of guinea pigs.
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Keywords
antihypertensive drug, allergenic effect, bisoprolol, lisinopril, indapamide
Citation
Molotyagin D. Experimental research of allergenic effect of coformulated antihypertensive drug / D. Molotyagin // Naukowa przestrzeń Europy : materiały XII międzynarodowej naukowi-praktycznej konferencji, 7–15 kwietnia 2016. – Przemysl (Poland), 2016. – Vol. 10 : Medycyna, Nauk biologicznych. – S. 5–6.