Transforming growth factor β1 in the development of left ventricular diastolic dysfunction in patients with chronic obstructive pulmonary disease combined with arterial hypertension

Abstract

The aim – to investigate the importance of transforming growth factor β1 (TGF-β1) in diastolic heart failure in patients with chronic obstructive pulmonary disease (COPD) combined with arterial hypertension (AH). Conclusions. Increased TGF-β1 in patients with AH and COPD contributes to the impaired relaxation of the left ventricle, when progression of diastolic heart failure is associated with atendency of TGF-β1 decrease.

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Dielievska V. Yu. Transforming growth factor β1 in the development of left ventricular diastolic dysfunction in patients with chronic obstructive pulmonary disease combined with arterial hypertension / V. Yu. Dielievska // Український кардіологічний журнал. – Додаток 1: Матеріали XVI Національного конгресу кардіологів України, 23–25 вересня 2015 р. – С. 56–57.

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