Arterial hypertension and non-alcoholic fatty liver disease: adipokine activity

Abstract

The leptin level, TNF-α and the HOMA-IR index (leptin 12.73±0.82 ng/ml, female patients: 12.93±0.99 ng/ml, male patients: 11.92±1.23 ng/ml; TNF-α 8.40±0.44 mg/ml; HOMA-IR index 4.09±0.49 CU) were significantly higher in the patients patients with AH and NAFLD with AO than such of the patients with AH and NAFLD without AO: (leptin 6.66±0.48 ng/ml, female patients: 6.25±1.19 ng/ml, male patients: 6.78±0.53 ng/ml; TNF-α 5.31±0.37 ng/ml; HOMA-IR index 2.0±0.22 CU). Conclusion. The levels of leptin, TNF-α and insulin resistance index were elevated statistically significant in patients with AH and NAFLD with AO.