Clinical significance of Von Willebrand factor and monocyte chemoattractant protein 1 in children with Henoch-Schonlein purpura

Abstract

Henoch-Scho ̈nlein purpura (HSP) is the most common small vessel vasculitis in childhood. Usually, the first laboratory signs of renal syndrome development in the case of HSP found at 3-4 weeks from the onset of the disease. Henoch-Schonlein purpura nephritis (HSPN) is identified increasingly as the main cause of chronic renal failure among children, 5-15% of children with HSPN develop chronic renal failure.