Role of adipose tissue hormones in the development of the metabolic disorders in patients with arterial hypertension and diabetes mellitus type 2

Abstract

The results of our investigation showed that the level of adiponectin was 29,15% significantly lower in patients with comorbidity of arterial hypertension and diabetes mellitus type 2 compared to hypertensive patients without diabetes and 62.55 % lower than in the control group (p < 0.001). Whereas the level of resistin, on the contrary, was 21.58 % significantly higher in patients with arterial hypertension and diabetes mellitus type 2 compared to patients without diabetes and 48% higher than in the control group (p < 0.001). These results suggest that adipocytokines are the factors of the insulin resistance development in patients with arterial hypertension and diabetes mellitus type 2.