Browsing by Author "Batyuk, Liliya"

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A comparison of the dielectric properties of hemoglobin before and after radiotherapy
(2019-06-18) Batyuk, Liliya; Berest, Volodumir
The dielectric properties of aqueous hemoglobin solutions of donors and oncological patients are investigated under a variety of parameters, and the results are discussed in terms of the most probable orientation polarization.
Adapting to the conditions of Ukraine the best world experience in the health of the nation: challenges and prospects
(Інститут гуманітарних і соціальних наук Національного університету «Львівська політехніка», 2021-06-16) Batyuk, Liliya; Chovpan, Ganna
The following world best practices for the development and improvement of the nation's health have been singled out for further adaptation to Ukraine's conditions: the main function of the state is to create a motivational space for citizens to take responsibility for their own health (modern German and French policies); creation of a network of rehabilitation institutions (rehabilitation centers), a network of palliative care institutions in district centers (Latvian experience); a new tender policy that will improve patient outcomes and create value in the health care system (the experience of the UK, Spain, Canada, the Netherlands and other countries); providing psychological care to seriously ill patients not only in specialized medical institutions, but also in centers, organized by charitable and public organizations (USA); introduction of the Standard according to which the rehabilitation of patients (helping patients to adapt and develop skills and ability to be independent in society, improving their quality of life) can be preventive, restorative, supportive and palliative (EU).
Algorithm for making decisions based on fuzzy network models in problems of medical diagnostics and forecasting
(Київський політехнічний інститут імені Ігоря Сікорського, 2021-04-21) Batyuk, Liliya; Chovpan, Ganna
The proposed algorithm for solving the problem to diagnose the addition of secondary bacterial pneumonia and to prescribe antibiotic therapy in a timely manner in patients with COVID-19 can be used for the problem of decision making, in which the values of local criteria are characterized by blur.
Assessment of Protein Fractions of RBCs in Stroke under Influence of Nanodiamonds in vitro
(Institute of Electrical and Electronics Engineers, 2018-09-09) Batyuk, Liliya; Kizilova, Natalya; Muraveinik, Oksana
Nanodiamonds have unique properties and demonstrate exceptional performance in various fields of investigation and biotechnology, especially in medicine as drug delivery system. Quantitative changes in the red blood cell (RBC) membrane proteins in acute ischemic stroke patients have been studied. The increased amount of ankyrin 2.4, 2.5 fractions, protein of band 3, protein of band 4.1, 4.2 and 4.9 fractions, protein of band 6, tropomyosin (protein of band 7) and protein of band 8 in patients with ischemic stroke have been detected. Increase in the content of spectrin, fractions 2.2, 2.3 (ankyrin), protein of band 2.5, 4.1, glucose transporter and protein of band 8, and decrease in the protein of band 4.2, 4.9 and an increase in the protein of band 4.2, 4.9 and p5 protein of band 5 (actin) from the samples with the nanodiamonds added have been observed. It is concluded that nanodiamonds plays an important role in regulation of the quantitative misbalances of the erythrocyte membrane proteins in the patients with acute ischemic stroke.
Bases of medical information science : Lecture 1
(2019-02-04) Batyuk, Liliya; Knigavko, Volodymyr; Chovpan, Hanna
Multimedia presentation on “Medical informatics” for international students (2018-2019 ac.year).
Biophysical biomarkers of human erythrocytes for efficient diagnostics of stroke
(Riga, Latvia: Baltija Publishing, 2022-10) Batyuk, Liliya; Kizilova, Nataliya
Timely and reliable diagnostics of acute and severe diseases like cancer, stroke and myocardial infarction is of a great importance for human health. Biophysical parameters of the red blood cells (RBC) can be used as biomarkers for early diagnosis together with chemical biomarkers and clinical tests. Compared to the latter, the studies on the blood sample are easier accessible and cheaper. The purpose of the paper is to demonstrate the high sensitivity of the dielectric properties of single RBC to the general chemical composition of the blood plasma due to the disease development and the available medical technique for their measurements based on the clinical studies. Methodology of the study is based on experimental measurements on the blood samples of healthy donors (control group) and patients with ischemic and hemorrhage stroke (experimental group) in the electromagnetic feld of microware frequencies at diﬀerent temperatures between T=0C and 54C. Results confrmed early noticeable inﬂuence of the disease on the real and imaginary part of complex dielectric permittivity of the REC and their membranes than can be easily detected by the microwave dielectric spectroscopy (MDS). The variations in the dielectric parameters tend to zero after a successful treatment that can be used as an additional biomarker of a proper individual treatment of the disease. Practical implications. The MDS method in a range of temperatures can be recommended for early diagnostics of the disease severity and estimation of the treatment efciency. The method is fast, simple and cheap, and it needs a sample of the venous blood only. Value/originality. The eﬀectiveness of the proposed method is based on a series of experimental studies and theoretical modeling and gives a new insight to the importance of dielectric properties of RBC that are the most movable cells in our bodies which carries on their membranes the inﬂuences of all biochemical markers produced by the disease.
Chemiluminescence analysis of drug resistance of the recombinant tissue plasminogen activator
(Институт биофизики и клеточной инженерии НАН Беларуси, 2021-05-20) Batyuk, Liliya; Muraveinik, Oksana; Kizilova, Nataliya
The aim of this work was to study the biochemiluminescence of blood serum and whole blood in patients who were prescribed rtPA (at a dose of 0.9 mg/kg, the maximum dose was 90 mg) during the first 3 hours after the onset of neurological symptoms (onset of IS).
Complex flows of cellular suspensions in microtubes at different temperatures
(2017-10-23) Kizilova, Nataliya; Batyuk, Liliya
Steady flow of a viscoplastic suspension of RBCs through a microtube at different temperatures has been studies. The temperature dependencies of the material parameters as well as the Fåhræus– Lindqvist and Copley-Scott Blair phenomena have been taken into account. The measurement data have been discussed based on the theoretical results.
Complex permittivity measurement of erythrocytes at a frequency of 9.2 GHz by resonator method
(Міністерство Освіти і Науки України, Кременчуцький національний університет імені Михайла Остроградського, 2016-11-07) Batyuk, Liliya; Kizilova, Nataliya; Astapovich, Dmitrii; Berest, Volodumir
Дана робота спрямована на створення бази діелектричних властивостей еритроцитів в нормі та при різних захворюваннях на основі вимірювань комплексної діелектричної проникності методом СВЧ-діелектрометрії. Значення дійсної діелектричної проникності було визначене шляхом вимірювання резонансної частоти резонатора відносно порожнього резонатора. Значення уявної діелектричної проникності знаходили за величиною згасання потужності СВЧ поля при введені діелектричного розчину в резонатор.
Current State and Prospects of Bioinformatics Development
(Інститут молекулярної біології і генетики Національної академії наук України, 2019-05-22) Morozova, Oksana; Chovpan, Hanna; Batyuk, Liliya
Analization of the state of bioinformatics as a branch of science and founding of prospects of its developmemt
Decision-making in medicine : Lecture 3
(Kharkiv National Medical University, 2019-01-05) Batyuk, Liliya; Knigavko, Volodymyr; Chovpan, Hanna
Multimedia presentation on “Medical informatics” for international students (2018-2019 ac.year).
Dependence of Superconducting Properties of YBa2Cu3O7-d - crystal on the Structure of the Crystal Lattice.
(B. Verkin Institute for Low Temperature Physics and Engineering (ILTPE) of NAS of Ukraine, 2020-06-10) Morozova, O.; Batyuk, Liliya
The influence of changes in the crystal lattice structure of the high-temperature superconductor on the conductive properties has been studied in this work
Development of medical information science competences for English-speaking foreign students at the Department of Medical and Biological Physics and Medical Informatics
(Dnipro National University, 2019-03-29) Knigavko, Volodymyr; Zaytseva, O.; Bondarenko, Maryna; Rukin, O.; Ponomarenko, N.; Batyuk, Liliya; Morozova, O.
At the Department of Medical and Biological Physics and Medical Informatics of the Kharkiv National Medical University the discipline "Medical Informatics" is taught to English-speaking foreign students (over 1000 students), as well as to the state language students, on the second year. Recently, the department reoriented the teaching methodology from a knowledge-based approach to a competence (knowledge-based plus practical skills) one, that is a condition of modernization and bringing its results in accordance to international standards. Competence approach not only makes the student aware, but also determines the development of skills to solve problems that arise in real situations. Earlier in the department this discipline was taught exclusively in the form of seminars. Currently, students' training is carried out in four computer classrooms in the form of computer practical works.
Development of modern nanotecnologies and combined biotoxicity problems
(2022-09-30) Batyuk, Liliya; Kizilova, Nataliya
Fast progress in modern nanotechnologies based on use of nanoparticles, nanofibers and nanotubes with different composition, shape and size allows elaboration of materials with superhigh strength, thermal and electric conductivity, acoustical and optical properties. Those materials are already widely used in industry, transportation, aerospace, marine and civil engineering, food processing and medicine. Some examples of nanoreinforces composites, superhydrophobic self-cleaning surfaces, nanodyes and suspensions of nanoparticles are described. The problem of uncontrolled accumulation of some types of nanoparticles in our cells and tissues is discussed within the concept of nanotoxicity. Since the history of permanent observation of human health in connection with nanodust accumulation in the atmosphere, waters and soils is not enough long, the detailed evidences must be documented, systematized and discussed. In this study a brief systematic review of literature on the biotoxicity problems caused by modern nanotechnologies is given. Production of the nanoparticles, nanofibers and nanotubes for industry, transportation, food processing, as well as utilization of the used materials which properties were modified by the nanotechnologies leads to permanent rise of the nanodust in the atmosphere, soils, river waters, lakes and the sea bottom. Their uncontrolled interaction with flora and fauna could be catastrophic for human health and life on the Earth. Promising ways for the problem solution and perspectives are discussed. Some own results on the protective action of nanodiamonds, silver and some other nanoparticles are presented. A vital necessity of an open access database on known types of nanoparticles, their use in the materials and documented influence of health of animals and humans is discussed.
The development trend of the medical services market in Ukraine: the European integration experience of Estonia
(Національний університет «Львівська політехніка», 2021-05-27) Batyuk, Liliya; Chovpan, Ganna
Comparing the European integration experience of the Eastern European countries and the Baltic countries. The process of reforming medicine in Ukraine it possible to consider opportunities and goals the market development trends segment of private medical services in Ukraine.
Dielectric characteristics of blood cell as biomarkers for diagnostics: experimental data and mathematical modelling
(2021-10-04) Batyuk, Liliya; Kizilova, Nataliya
It is shown, the dielectric properties of RBCs, their membranes (water-filled shells) and blood with different RBC concentrations can be considered as biomarkers that are unique for the breast and lung cancer, different disease stage and treatment applied.
Dielectric parameters for cell model calculation
(Белорусский государственный медицинский университет, 2021-05-21) Batyuk, Liliya; Kizilova, Nataliya
This paper presents a brief description of mathematical modeling, which describes the effective dielectric constant of a suspension of erythrocytes, for the cases f three geometric shapes, when the erythrocyte is considered as a dispersed particle.
Dielectric properties of hemoglobin in microwave region: Influence of oncology and radiation therapy
(2019-09-15) Batyuk, Liliya; Berest, Volodumir; Kizilova, Nataliya
Investigation of dielectric characteristics of aqueous hemoglobin solutions of erythrocytes in temperature area from 15 to 36 °C the patients with breast and lung cancer was had carried.
Dielectric properties of micro/nanoparticles suspensions at low and room temperatures: a thermodynamic approach
(B. Verkin Institute for Low Temperature Physics and Engineering (ILTPE) of the NAS of Ukraine, 2018-06-04) Batyuk, Liliya; Kizilova, Nataliya; Baranets, V.
The measurement data on the dielectric parameters of suspensions of human erythrocytes, aqueous suspensions of ND, and rat erythrocytes with ND at the low and room temperatures have been used for understanding the physical phenomena in the MP and NP suspensions in high frequency external MW fields. It is shown that the hydrated shells of the MP and NP are influenced by the particle geometry, curvature of the interfaces, relaxation phenomena in the MW fields, and ambient temperature.
Dielectric properties of nanoparticle suspensions at low temperatures: a thermodynamic of solution hydration
(2019-06-03) Batyuk, Liliya; Morozova, O.; Kizilova, Nataliya
Based on created this model, we have analyzed the effect of temperature on the dielectric dispersion curves of red blood cells in suspension. All the parameters of the model have distinct influences on the dispersion curves, a fact that lead us to conclude that all the parameters can be accurately obtained by fitting experimental data with our model.