Please use this identifier to cite or link to this item:
http://repo.knmu.edu.ua/handle/123456789/31155
Title: | Effect of eplerenone on serum level of soluble growth-stimulating receptor expressed by gene 2 in patients with arterial hypertension |
Authors: | Bilovol, O. Knyazkova, I. Golovacheva, V. Kuzminova, N. Barbashova, V. Molodan, D. Bogun, N. |
Keywords: | hypertension eplerenone diastolic dysfunction echocardiography soluble growth-stimulating receptor expressed by gene 2,N-terminal fragment of brain natriuretic propeptide |
Issue Date: | 2022 |
Citation: | Effect of eplerenone on serum level of soluble growth-stimulating receptor expressed by gene 2 in patients with arterial hypertension / O. M. Bilovol, I. I. Knyazkova, V. O. Golovacheva, N. V. Kuzminova, V. O. Barbashova, D. V. Molodan, M. V. Bogun // World of Medicine and Biology. – 2022. – № 3 (81). – P. 26–31. – DOI: 10.26724/2079-8334-2022-3-81-26-31. |
Abstract: | The purpose of the work was to study the dynamics of diastolic function parameters, the content of the soluble growth-stimulating receptor expressed by gene 2 (sST2) and the N-terminal fragment of the brain natriuretic propeptide (NT-proBNP) in the blood of patients with hypertension, when eplerenone is added to antihypertensive therapy. In patients with stage 2 arterial hypertension, addition of eplerenone to antihypertensive therapy contributes to a more pronounced decrease of blood pressure measured by patients during self-monitoring; during daily monitoring compared to antihypertensive therapy. The inclusion of the selective aldosterone mineralocorticoid receptor antagonist eplerenone in the complex therapy of patients with stage 2 arterial hypertension has a pronounced positive effect on the structural and geometric indicators of the myocardium, parameters of the diastolic function of the left ventricle, as well as the content of sST2 and NT-proBNP in the blood serum, along with good tolerability. |
URI: | http://repo.knmu.edu.ua/handle/123456789/31155 |
Appears in Collections: | Наукові праці. Кафедра клінічної фармакології та внутрішньої медицини Наукові праці. Кафедра педіатрії № 2 |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Bilovol et al_Effect of Eplerenone.pdf | 260,42 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.