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DC Field | Value | Language |
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dc.contributor.author | Bilovol, O. | - |
dc.contributor.author | Knyazkova, I. | - |
dc.contributor.author | Golovacheva, V. | - |
dc.contributor.author | Kuzminova, N. | - |
dc.contributor.author | Barbashova, V. | - |
dc.contributor.author | Molodan, D. | - |
dc.contributor.author | Bogun, N. | - |
dc.date.accessioned | 2022-11-26T17:24:33Z | - |
dc.date.available | 2022-11-26T17:24:33Z | - |
dc.date.issued | 2022 | - |
dc.identifier.citation | Effect of eplerenone on serum level of soluble growth-stimulating receptor expressed by gene 2 in patients with arterial hypertension / O. M. Bilovol, I. I. Knyazkova, V. O. Golovacheva, N. V. Kuzminova, V. O. Barbashova, D. V. Molodan, M. V. Bogun // World of Medicine and Biology. – 2022. – № 3 (81). – P. 26–31. – DOI: 10.26724/2079-8334-2022-3-81-26-31. | en_US |
dc.identifier.uri | http://repo.knmu.edu.ua/handle/123456789/31155 | - |
dc.description.abstract | The purpose of the work was to study the dynamics of diastolic function parameters, the content of the soluble growth-stimulating receptor expressed by gene 2 (sST2) and the N-terminal fragment of the brain natriuretic propeptide (NT-proBNP) in the blood of patients with hypertension, when eplerenone is added to antihypertensive therapy. In patients with stage 2 arterial hypertension, addition of eplerenone to antihypertensive therapy contributes to a more pronounced decrease of blood pressure measured by patients during self-monitoring; during daily monitoring compared to antihypertensive therapy. The inclusion of the selective aldosterone mineralocorticoid receptor antagonist eplerenone in the complex therapy of patients with stage 2 arterial hypertension has a pronounced positive effect on the structural and geometric indicators of the myocardium, parameters of the diastolic function of the left ventricle, as well as the content of sST2 and NT-proBNP in the blood serum, along with good tolerability. | en_US |
dc.language.iso | en | en_US |
dc.subject | hypertension | en_US |
dc.subject | eplerenone | en_US |
dc.subject | diastolic dysfunction | en_US |
dc.subject | echocardiography | en_US |
dc.subject | soluble growth-stimulating receptor expressed by gene 2,N-terminal fragment of brain natriuretic propeptide | en_US |
dc.title | Effect of eplerenone on serum level of soluble growth-stimulating receptor expressed by gene 2 in patients with arterial hypertension | en_US |
dc.type | Article | en_US |
Appears in Collections: | Наукові праці. Кафедра клінічної фармакології та внутрішньої медицини Наукові праці. Кафедра педіатрії № 2 |
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Bilovol et al_Effect of Eplerenone.pdf | 260,42 kB | Adobe PDF | View/Open |
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