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http://repo.knmu.edu.ua/handle/123456789/30907
Title: | Influence of a hypocaloric diet on the parameters of nonspecific humoral immunity in rats |
Authors: | Pavlova, Olena Sirenko, Victor |
Keywords: | cytokines nonspecific immunologic reactivity pancreas |
Issue Date: | 17-Jan-2022 |
Citation: | Pavlova О. Influence of a hypocaloric diet on the parameters of nonspecific humoral immunity in rats / О. Pavlova, V.A. Sirenko // Modern systems of science and education in the USA, EU and other countries ‘2022 : International scientific conference, Seattle, Washington, USA, January, 2022 : conference proceedings. – Seattle; Washington, 2022. – P. 32–34. – DOI: 10.30888/2709-2267.2022-09-01-019. |
Abstract: | Have been considered the role of the imbalance of regulatory cytokines in the blood in the implementation of immune responses in rats that were on a hypocaloric diet, compared with the control, where was established: a predominant increase in the content of IL-12, a decrease in IL-4 in rats, which indicates the participation of both specific (Th 1), and non-specific (macrophage), cellular immunity in the mechanisms of damage to the pancreas and the development of chronic pancreatitis in the future. The latter is probably associated with a violation of intercellular interaction due, first of all, to a decrease in the functional activity of macrophages - effector cells, modulators of the immune response, and sources of regulatory cytokines. |
URI: | http://repo.knmu.edu.ua/handle/123456789/30907 |
Appears in Collections: | Наукові праці. Кафедра загальної та клінічної патофізіології імені Д.О. Альперна |
Files in This Item:
File | Description | Size | Format | |
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Pavlova O. Sirenko V._Influence of a hypocaloric.pdf | 4,35 MB | Adobe PDF | View/Open |
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