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http://repo.knmu.edu.ua/handle/123456789/19368
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DC Field | Value | Language |
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dc.contributor.author | Syrova, Ganna | - |
dc.contributor.author | Lukianova, Larysa | - |
dc.contributor.author | Chalenko, Natalia | - |
dc.date.accessioned | 2018-04-04T12:54:28Z | - |
dc.date.available | 2018-04-04T12:54:28Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Syrova G. O. The experimental research on the antiinflammatory action of the new piroxicamcaffeine pharmaceutical composition / G. O. Syrova, L. V. Lukianova, N. M. Chalenko // Science Review. – 2018. – Vol. 4, № 3(10). – P. 72–76. | ru_RU |
dc.identifier.uri | https://repo.knmu.edu.ua/handle/123456789/19368 | - |
dc.description.abstract | Conducting an experimental research on laboratory rats subjected to endogastric injections, our scientists have explored the influence of the non-steroid anti-inflamatory drug from the oxicam group piroxicam (4-hydroxo-2-methyl-N-pyridine-2-il)-2H-1,2-benzothiazine-3-carboxamide1,1- dioxyde), a well-known adjuvant of non-narcotic analgetics and non-steroid anti-inflamatory drugs such as caffeine (1,3,7-trimethylxanthine)and the two-component piroxicam-caffeine pharmaceutical composition on the rats’ anti-exudative activity under formalin edema. The analysis of the results of the experimental researches points to the fact that caffeine promotes the anti-exudative action of piroxicam in the rats under formalin edema. The above-mentioned experimental researches allow us to come to the conclusion that due to its vasoconstrictive effect caffeine performs as an adjuvant to piroxicam (a non-steroid anti-inflamatory drug from the oxicam group) concerning the anti-exudative activity. The results of the research can become a basis for the development of new combined drugs in Ukraine. | ru_RU |
dc.language.iso | en | ru_RU |
dc.subject | piroxicam | ru_RU |
dc.subject | caffeine | ru_RU |
dc.subject | pharmaceutical composition | ru_RU |
dc.subject | anti-inflammatory effect | ru_RU |
dc.subject | formalin edema | ru_RU |
dc.title | The experimental research on the antiinflammatory action of the new piroxicamcaffeine pharmaceutical composition | ru_RU |
dc.type | Article | ru_RU |
Appears in Collections: | Наукові праці. Кафедра медичної та біоорганічної хімії |
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Syrova_experimental research.pdf | 379,44 kB | Adobe PDF | View/Open |
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