Dental status of patients during the supportive care at antineoplastic chemotherapy for breast cancer

Abstract

Two groups were studied in a comparative aspect – 98 women with breast cancer during the courses of adjuvant chemotherapy: the first was comprised of 26 patients who used their conventional means for oral hygiene; the second included 72 patients, who received the complex of therapeutic and preventive measures of supportive care. Dental toxicity was observed in 84.6-96.2 %, and has grown with the increase of the cycles of chemotherapy, reaching a maximum value on the V cycle of treatment. It is shown that the application of the developed complex significantly reduces the manifestations of dental toxicity by 1.5 times on the I cycle and by 4.5 times on the VI cycle of chemotherapy.