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http://repo.knmu.edu.ua/handle/123456789/33173| Title: | Breast cancer relapses considering molecular biological characteristics |
| Authors: | Smolanka, Ivan Movchan, Oleksii Bagmut, Irina Sheremet, Michael Kolisnyk, Igor Dosenko, Irina Lyashcnko, Andriy Ivankova, Oksana Loboda, Anton Shidlovsky, Oleksandr |
| Keywords: | breast cancer relapse molecular-biological properties of tumors risk factors 2023а |
| Issue Date: | 2023 |
| Publisher: | Journal of medicine and life |
| Citation: | Breast cancer relapses considering molecular biological characteristics / I. I. Smolanka, O. V. Movchan, I. L. Kolisnyk [et al.] // Journal of medicine and life. ─ 2023. ─ Vol. 16, № 1. ─ P. 70─75. |
| Abstract: | We aimed to analyze the frequency of breast cancer relapses and their relationship with molecular and biological tumor characteristics. We studied 6,136 breast cancer patients, including 146 with relapses (Group 1) and 455 without relapses (Group 2). We divided the patients based on age, menstrual function, disease stage, histology form and grade, and molecular-biological subtype. The 5-year relapse-free rate for Group 1 was longer for Lum A and TN subtypes (60% and 40%, respectively) but shorter for Lum B and HER-2/neu-amplified subtypes (38% and 31%, respectively). Disease stage, tumor histology, and grade did not significantly affect relapse frequency in these patients. Relapses were more common in premenopausal patients and the Lum B subtype. |
| URI: | http://repo.knmu.edu.ua/handle/123456789/33173 |
| Appears in Collections: | Наукові праці. Кафедра анатомії людини, клінічної анатомії та оперативної хірургії |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| 13.-jml-2022-0189.pdf | 246,28 kB | Adobe PDF | View/Open |
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