Please use this identifier to cite or link to this item:
http://repo.knmu.edu.ua/handle/123456789/32818
Title: | Association of Country Income Level With the Characteristics and Outcomes of Critically Ill Patients Hospitalized With Acute Kidney Injury and COVID-19 |
Authors: | Gavrylov, Anatoliy Tieroshyn, Vadym Wainstein, M. Spyrison, Nicholas Dai, Danyang Ghadimi, Moji Chávez-Iñiguez, Jonathan S. Rizo-Topete, Lilia Citarella, Barbara Wanjiru Merson, Laura Pole, Jason D. Claure-Del, Granado Rolando Johnson, David W. Shrapnel, Sally |
Keywords: | acute kidney injury community-acquired AKI country income COVID-19 dialysis in-hospital death 2023а |
Issue Date: | Aug-2023 |
Citation: | Association of Country Income Level With the Characteristics and Outcomes of Critically Ill Patients Hospitalized With Acute Kidney Injury and COVID-19 / M. Wainstein, N. Spyrison, D. Dai [et al.] // Kidney International Reports. – 2023. ─ Vol. 8. ─ P. 1514─1530. |
Abstract: | Introduction: Acute kidney injury (AKI) has been identified as one of the most common and significant problems in hospitalized patients with COVID-19. However, studies examining the relationship between COVID-19 and AKI in low- and low-middle income countries (LLMIC) are lacking. Given that AKI is known to carry a higher mortality rate in these countries, it is important to understand differences in this population. Methods: This prospective, observational study examines the AKI incidence and characteristics of 32,210 patients with COVID-19 from 49 countries across all income levels who were admitted to an intensive care unit during their hospital stay. Results: Among patients with COVID-19 admitted to the intensive care unit, AKI incidence was highest in patients in LLMIC, followed by patients in upper-middle income countries (UMIC) and high-income countries (HIC) (53%, 38%, and 30%, respectively), whereas dialysis rates were lowest among patients with AKI from LLMIC and highest among those from HIC (27% vs. 45%). Patients with AKI in LLMIC had the largest proportion of community-acquired AKI (CA-AKI) and highest rate of in-hospital death (79% vs. 54% in HIC and 66% in UMIC). The association between AKI, being from LLMIC and in-hospital death persisted even after adjusting for disease severity. Conclusions: AKI is a particularly devastating complication of COVID-19 among patients from poorer nations where the gaps in accessibility and quality of healthcare delivery have a major impact on patient outcomes. |
URI: | http://repo.knmu.edu.ua/handle/123456789/32818 |
Appears in Collections: | Наукові праці. Кафедра дитячих інфекційних хвороб |
Files in This Item:
File | Description | Size | Format | |
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Kidney International Reports.pdf | 1,25 MB | Adobe PDF | View/Open |
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