Please use this identifier to cite or link to this item: http://repo.knmu.edu.ua/handle/123456789/32721
Title: State of the Blood-Air Barrier in Pediatric Acute Leukemia patients: prognosis for pulmonary complications
Authors: Makieieva, Natalia
Koval, Victoria
Keywords: acute leukemia
pneumonia
children
pulmonary complications
blood-air barrier
cytokines
interleukin-6
transforming growth factor β
vascular endothelial growth factor
2023а
Issue Date: 2023
Citation: Makieieva N. I. State of the Blood-Air Barrier in Pediatric Acute Leukemia patients: prognosis for pulmonary complications / N. Makieieva, V. Koval // Hematology/Oncology : 8th Kaunas/Lithuania International Colloquium, 12 th May, 2023, Kaunas, Lithuania : Online Poster Abstract Book. – Kaunas, 2023. ─ P. 15─17.
Abstract: The blood-air barrier (BAB) is a structural and functional part of the lungs, which is composed of epithelial, interstitial, and endothelial components. Studied markers IL-6, TGF-β in exhaled breath condensate (EBC) and serum VEGF-A are increased both during protocol treatment and in long-term remission, which proves BAB damage in children with acute leukemia (AL). Levels of IL-6 and TGF-β in EBC and VEGF-A in serum can be predictive for lung complications in pediatric acute leukemia patients. Assessment of BAB damage markers can be useful for the management of children with AL to provide timely and effective care.
URI: http://repo.knmu.edu.ua/handle/123456789/32721
Appears in Collections:Наукові праці. Кафедра педіатрії № 2

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