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Title: | Вehavioral reactions and cognitive functions in rats with vascular model of alzheimer's type dementia at the different stages of disease before and after stem cell correction |
Other Titles: | Поведінкові реакції та когнітивні функції у щурів з судинною деменцією альцгеймерівського типу в різні терміни захворювання до та після корекції стовбуровими клітинами |
Authors: | Lukyanova, Yevgeniya Nikolaeva, Olga Pavlova, Olena Vasyleva, Iryna Naglov, Olexander Shchegelskaya, Elena Omelchenko, Elena |
Keywords: | stem cells rats alzheimer’s disease sodium nitrite cognition behavior brain |
Issue Date: | 2020 |
Citation: | Вehavioral reactions and cognitive functions in rats with vascular model of alzheimer's type dementia at the different stages of disease before and after stem cell correction / Y. Lukyanova, О. Nikolaeva, О. Pavlova, I. Vasyleva, О. Naglov, Е. Shchegelskaya, Е. Omelchenko // Inter collegаs. – 2020. – Vol. 7, N 3. – Р. 118–124. |
Abstract: | In all experimental groups in most cases it was found the significant decrease in vertical and horizontal activity (p <0,05) and an increase in the number of defecation in the OFT. Rats from group 3 had the drop in locomotor, research and orientation activity. In the OFT and PAT in groups 2,4 it was observed an improvement in research activity and significant cognitive functions recovery (p=0,012) after stem cell correction. It was found the progression of the protective inhibition and cognitive impairment during experiment. The stem cells introduction had positive effects on brain function recovery |
URI: | https://repo.knmu.edu.ua/handle/123456789/27590 |
Appears in Collections: | Наукові праці. Кафедра загальної та клінічної патофізіології імені Д.О. Альперна |
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интер коллегас лукьянова.docx | 41,36 kB | Microsoft Word XML | View/Open |
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