Relationship between adiponectin and anthropometric parameters, insulin resistance and transaminase levels in patients with nonalcoholic fatty liver disease and type 2 diabetes

Abstract

The basis of the pathogenesis of nonalcoholic fatty liver disease (NAFLD) is insulin resistance (IR) which appears on the background of abdominal obesity (AO) which, in turn, is a key factor in the emergence of an imbalance between adipocytokines entailing a disturbance of lipid and carbohydrate metabolism, which ultimately leads to the damage of the liver cells, the development of inflammation, fibrosis and apoptosis.