Please use this identifier to cite or link to this item:
http://repo.knmu.edu.ua/handle/123456789/818
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Detistov, Oleksandr | - |
dc.contributor.author | Orlov, V. | - |
dc.contributor.author | Zhuravel`, I. | - |
dc.date.accessioned | 2012-09-19T07:10:58Z | - |
dc.date.available | 2012-09-19T07:10:58Z | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | Detistov O. S. Іsomeric 3-isoxadiazolylcoumarins and their derivatives / O. S. Detistov, V. D. Orlov, I. O. Zhuravel` // J. Heterocyclic Chem. – 2012. – Vol. 49. – P. 883–892. | uk_UK |
dc.identifier.issn | 0022-152X | - |
dc.identifier.uri | https://repo.knmu.edu.ua/handle/123456789/818 | - |
dc.description.abstract | Here we represent preparative methods of synthesis of isomeric 3-isoxadiazolylcoumarins and their derivatives. Two new synthetic methods have been developed for 3-[1,2,4-oxadiazol-5-yl]coumarins I. The first method is based on a three-component condensation of coumarin-3-carboxylic acids, CDI and amidoximes. The second method essentially uses the interaction of 5-cyanomethyl-1,2,4-oxadiazoles with salicylic aldehydes. General approach for preparation of 3-[1,2,4-oxadiazol-3-yl]coumarins II has been worked out. Moreover, above mentioned synthetic ways open the way for the synthesis of 2-iminoderivatives III and IV not described before, those were diversified by reaction of nucliophilic substitution of 2-imino group with a numerous amino compounds. | uk_UK |
dc.language.iso | en | uk_UK |
dc.publisher | Wiley | uk_UK |
dc.subject | 1,2,4-oxadiazole | uk_UK |
dc.subject | coumarins | uk_UK |
dc.subject | synthetic ways | uk_UK |
dc.title | Isomeric 3-isoxadiazolylcoumarins and their derivatives | uk_UK |
dc.type | Article | uk_UK |
Appears in Collections: | Наукові праці. Кафедра медичної та біоорганічної хімії |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
jhet893_published_d.pdf | 8,32 MB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.