Please use this identifier to cite or link to this item: http://repo.knmu.edu.ua/handle/123456789/6944
Title: Age-related peculiarities of change in content of free radical oxidation products in muscle during stress
Authors: Davydov, Vadim Vyacheslavovich
Hamdallah, Amjad
Grabovetskaya, Evgeniya Romanovna
Keywords: ontogenesis
stress
skeletal muscle
free radical oxidation
Issue Date: Aug-2014
Citation: Davydov V. V. Age-related peculiarities of change in content of free radical oxidation products in muscle during stress / V. V. Davydov, A. Hamdallah, E. R. Grabovetskaya // Frontiers in Biology. – 2014. – Vol. 9, issue 4. – P. 283–286.
Abstract: The age-dependent peculiarities of stimulation of free radical processes in subcellular fractions of skeletal muscle of rats subjected to long-term immobilization stress were studied in order to improve knowledge about changes of muscular tissue during ontogenesis. It is found that adult animals do not show accumulation of proteins carbonyls, TBA-reactive substances, and Schiff bases in subcellular fractions of the thigh muscle when immobilized. Long-term immobilization causes apparent manifestation of oxidative stress only in mitochondrial fraction in pubertal rats. Mitochondrial oxidative stress defense systems are sufficiently effective, however, direction of pathways of free radical oxidation carbonyl products catabolism alters in the cytoplasm of myocytes in old rats under long-term immobilization conditions.
URI: http://repo.knmu.edu.ua/handle/123456789/6944
ISSN: 1674-7992
Appears in Collections:Наукові праці. Кафедра медичної та біоорганічної хімії

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