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DC Field | Value | Language |
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dc.contributor.author | Riga, Olena | - |
dc.contributor.author | Khaustov, Maxym | - |
dc.contributor.author | Mikhaylova, Aleksandra | - |
dc.contributor.author | Orlova, Natalia | - |
dc.date.accessioned | 2023-10-19T18:52:53Z | - |
dc.date.available | 2023-10-19T18:52:53Z | - |
dc.date.issued | 2023-09 | - |
dc.identifier.citation | Vitamin D status in children with paralitic syndroms / O. Riga, M. Khaustov, A. Mikhaylova, N. Orlova // Wiadomości Lekarskie. – 2023. – Vol. LXXVI, issue 9. – P. 1984–1991. | en_US |
dc.identifier.uri | http://repo.knmu.edu.ua/handle/123456789/32669 | - |
dc.description.abstract | The aim: Determination of serum 25(OH)D in the children with paralytic syndromes and its distribution depending on age, sex, taking anticonvulsant drugs, nutritional status for a period of one year (autumn-spring) of one center. Materials and methods: There were recruited of 77 children with paralytic syndromes and 73 health children for the same period aged from 1 till 18 years. The study included a scrutiny of medical history and analysis of medical documents, assessment of motor dysfunction by GMFCS, and nutritional status. Results: Among children with paralytic syndromes there were spastic tetraparesis 59.7%, malnutrition 92%, IV-V level of gross motor disfunction 80.5%, antiseizure medications 59.7% and cognitive impairment 77.9%. The variation of serum 25(OH)D is from 6.1 to 76.7 ng/mL with median 18.3 ng/mL in healthy children. The variation of serum 25(OH)D is from 2.2 to 83.0 ng/mL with median 14.8 ng/mL in children with paralytic syndromes (p=0.0103). Vitamin status among them is the following: insufficiency (21–29 ng/mL)–28.7% vs 16.8%; deficiency (<20 ng/mL)–56.1 vs 72.2% (p=0.0300). The 25.9% children with paralytic syndromes and those who have deficiency demonstrate severe deficiency (<10 ng/mL) compare 10.9% in healthy children (p=0.00189). There is a tendency to decrease of serum 25(OH)D in children with paralytic syndrome older 7 years. Conclusions: We failed to record a significant difference in the 25(ОН)D between males and females, between different level of GMFCS, and anticonvulsants using. Deficiency of vitamin D in 2.25 times higher in children with paralytic syndromes and severe malnutrition. Additional researches with specific items are need in perspective. | en_US |
dc.language.iso | en | en_US |
dc.subject | children | en_US |
dc.subject | paralytic syndrome | en_US |
dc.subject | vitamin D deficiency | en_US |
dc.subject | COVID-19 | en_US |
dc.subject | 2023а | en_US |
dc.title | Vitamin D status in children with paralitic syndroms | en_US |
dc.type | Article | en_US |
Appears in Collections: | Наукові праці. Кафедра педіатрії № 1 та неонатології |
Files in This Item:
File | Description | Size | Format | |
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Vitamin D status in children with paralitic syndroms.pdf | 1,3 MB | Adobe PDF | View/Open |
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