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DC Field | Value | Language |
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dc.contributor.author | Kovalyova, Olga | - |
dc.contributor.author | Ковальова, Ольга Миколаїівна | - |
dc.contributor.author | Zhuravlyova, Anna | - |
dc.contributor.author | Журавльова, Анна Костянтинівна | - |
dc.contributor.author | Ivanchenko, Svitlana | - |
dc.contributor.author | Іванченко, Світлана Володимирівна | - |
dc.date.accessioned | 2023-10-07T15:57:56Z | - |
dc.date.available | 2023-10-07T15:57:56Z | - |
dc.date.issued | 2023 | - |
dc.identifier.citation | Kovalyova O. Renin-angiotensin system: a review of historical perspectives / O. Kovalyova, A. Zhuravlyova, S. Ivanchenko // Galician Medical Journal. – 2023. – № 30 (2). – P. 1–10. | en_US |
dc.identifier.uri | http://repo.knmu.edu.ua/handle/123456789/32578 | - |
dc.description.abstract | The article is a review of publications concerning historical perspectives of the renin-angiotensin system. The discovery of its components is presented in chronological order, beginning with the initial identification of renin and proceeding to the subsequent discoveries of angiotensin-converting enzyme 2, angiotensin-(1-7), Mas receptor. This paper presents a modern classification of the renin-angiotensin system, dividing it into classical and non-classical branches, based on the determination of the biological effects of its components. Significant attention is devoted to elucidating the biochemical cascade of the renin-angiotensin system, its physiological transformations, and its implications in human body processes. The detrimental cardiac effects of the classical renin-angiotensin system are highlighted, along with the crucial role played by its alternative axis in counteracting the development of cardiovascular diseases. The article presents data on the involvement of angiotensin-converting enzyme 2 and its receptors in coronavirus infections, susceptibility to infection, and disease progression. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Івано-Франківський національний медичний університет | en_US |
dc.subject | renin-angiotensin system | en_US |
dc.subject | angiotensin-converting enzyme | en_US |
dc.subject | angiotensin | en_US |
dc.subject | mas receptor | en_US |
dc.subject | 2023а | en_US |
dc.title | Renin-angiotensin system: a review of historical perspectives | en_US |
dc.type | Article | en_US |
Appears in Collections: | Наукові праці. Кафедра загальної практики – сімейної медицини та внутрішніх хвороб |
Files in This Item:
File | Description | Size | Format | |
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Галицкий медичний вісник.pdf | 910,14 kB | Adobe PDF | View/Open |
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