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http://repo.knmu.edu.ua/handle/123456789/29775
Title: | Dynamics of indicators of the endothelium morphofunctional state of the brain microcirculatory bed vessels in rats with nitrite-induced Alzheimer's type dementia on the background of mesenchymal stem cell administration or without it |
Authors: | Zorenko, Yevgeniya Gubina-Vakulyck, Galina Pavlova, Olena Gorbach, Tetyana Shchegelskaya, Elena Omelchenko, Elena |
Keywords: | alzheimer’s disease mesenchymal stem cells sodium nitrite |
Issue Date: | 2021 |
Citation: | Dynamics of indicators of the endothelium morphofunctional state of the brain microcirculatory bed vessels in rats with nitrite-induced Alzheimer's type dementia on the background of mesenchymal stem cell administration or without it / Y. М. Zorenko, G. I. Gubina-Vakulyck, O. O. Pavlova, T. V. Gorbach, E. A. Shchegelskaya, E. І. Omelchenko // Медицински часопис. – 2021. – Vol. 55, issue 1. – P. 18–26. |
Abstract: | The aim of this study was to assess the vascular endothelium morphofunctional state of the brain microcirculatory bed in rats with nitrite-induced Alzheimer's type dementia on the background of stem cells administration or without it. In animals with nitrite-induced dementia, dose-dependent damage to the endothelium of the capillary bed is noted. From the first day damage the vascular regeneration can be proved by VEGF expression. The stem cells administration more effectively stimulates capillary regeneration, as evidenced by a noticeable increase of the brain capillaries number. |
URI: | https://repo.knmu.edu.ua/handle/123456789/29775 |
Appears in Collections: | Наукові праці. Кафедра загальної та клінічної патофізіології імені Д.О. Альперна |
Files in This Item:
File | Description | Size | Format | |
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manuscript zorenko.doc | 133,5 kB | Microsoft Word | View/Open | |
титулка медчасописа.jpg | 101,08 kB | JPEG | View/Open |
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