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http://repo.knmu.edu.ua/handle/123456789/29580
Title: | Therapeutic efficacy of local treatment patients with I-II degrees of severity of chronic generalized periodontitis |
Authors: | Marchenko, Mariia Khudiakova, Maryna |
Keywords: | pro-inflammatory TNF-α anti-inflammatory IL-4 lecithin liposomes quercetin chronic generalized periodontitis |
Issue Date: | 20-Oct-2021 |
Citation: | Marchenko M. Therapeutic efficacy of local treatment patients with I-II degrees of severity of chronic generalized periodontitis / M. Marchenko, M. Khudiakova // ISIC-2021 : [International Scientific Interdisciplinary Conference for medical students and young scientists, Kharkiv, 20–21 October, 2021] : abstract book / KNMU. – Kharkiv, 2021. – P. 44–46. |
Abstract: | As a consequence, the considerate research of changes of pro-inflammatory TNF-α and anti-inflammatory ІL-4 cytokines might have considerable scientific and practical importance while treating patients with CGP of I-II degrees of severity with gel from the granules of Quercetinum (GQ) and liposomal Quercetinum-lecithin complex (LQLC). The purpose of study was to increase of efficiency of complex treatment the patients with CGP of I-II degrees of severity with gel from the granules of GQ and liposomal LQLC due to the correction of cytokine levels. In accordance to treatment all patients were divided into 2 groups: I group – basic treatment with local application LQLC (20 patients); II group (group of comparison (CG)) – basic treatment with local application of gel from GQ (18 patients). The cytokine level of the patients with I-II degrees of severity in the BG after twelve-month treatment was TNF-α-25,12±2 pg/ml, which was 77% lower than in the C and anti-inflammatory ІL-4 - 300,1±16,51 pg/ml, which was 2% higher. The cytokine level of the patients in the CG after twelve-month treatment was TNF-α-33,37±2,81 pg/ml, which was 54% lower than in the C and anti-inflammatory ІL-4-266,4±20,11 pg/ml, which was 23% lower than in the C. Considerable therapeutic efficacy of the LQLC for treatment patients with CGP, especially that of I-II degrees of severity is based on its marked anti-inflammatory, immunomodulating and periodontoprotecting effects. |
URI: | https://repo.knmu.edu.ua/handle/123456789/29580 |
Appears in Collections: | Наукові праці. Кафедра стоматології |
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File | Description | Size | Format | |
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ISIC2021_abstractbook-страницы-удалены (1).pdf | 375,22 kB | Adobe PDF | View/Open |
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