Caspase-dependent activation of cascade cytokines in young patients with autoimmune thyroiditis in combination with gastroesophageal reflux disease

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Date

2021

Authors

Pasiieshvili, Tamara
Pasiieshvili, Liudmyla
Zhelezniakova, Natalia
Kovalyova, Olga

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Abstract

The development of an inflammatory reaction in any disease of internal organs obeys to the basic law of inflammation – the participation of the immune system in its implementation.The sequence of the inclusion of its various components, the volume of the cellular and humoral response depends on many factors: the action and the virulence of the pathogen, the state of the immune system both in general and its individual links, concomitant diseases and a number of others.An inflammatory reaction is a genetically determined function of the body, aimed at maintaining homeostasis, that is, neutralizing the pathogen without significant consequences for the body.

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Keywords

autoimmune thyroiditis, gastroesophageal reflux disease, pathogenesis, caspase-1, interleukin-18

Citation

Caspase-dependent activation of cascade cytokines in young patients with autoimmune thyroiditis in combination with gastroesophageal reflux disease / T. Pasiieshvili, L. Pasiieshvili, N. Zhelezniakova, O. Kovalyova // EUREKA: Health Sciences. – 2021. – N 1. – P. 58–63.