Please use this identifier to cite or link to this item: http://repo.knmu.edu.ua/handle/123456789/27979
Title: Features of the Severity of Cardiovascular Remodeling and Metabolic Disorders in Hypertensive Patients with Obesity in the Presence of Two Unfavorable Genotypes of the ADIPOQ and IRS-1 Genes
Authors: Shalimova, Anna
Psarova, Valentyna
Kyrychenko, Nataliia
Kochuieva, Maryna
Keywords: diabetes mellitus
metabolic disorders
obesity
hypertension
Issue Date: 2020
Citation: Features of the Severity of Cardiovascular Remodeling and Metabolic Disorders in Hypertensive Patients with Obesity in the Presence of Two Unfavorable Genotypes of the ADIPOQ and IRS-1 Genes / A. Shalimova, V. Psarova, N. Kyrychenko, M. Kochuieva // Journal of the Endocrine Society. – 2020. – Vol. 4, Abstract Supplement. – A35–A36.
Abstract: The results of a number of studies have shown that in ar- terial hypertension (AH), G/T and T/T genotypes of the adiponectin gene (ADIPOQ) and Gly/Arg and Arg/Arg genotypes of the insulin receptor substrate 1 gene (IRS-1) are associated with a greater severity of metabolic disorders and hemodynamic parameters compared with G/G and Gly/ Gly genotypes of these genes. The aim of the study: to evaluate the severity of cardiovas- cular remodeling and metabolic disorders in hypertensive obese patients in the simultaneous presence of two unfa- vorable genotypes of the ADIPOQ and IRS-1 genes.
URI: https://repo.knmu.edu.ua/handle/123456789/27979
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