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http://repo.knmu.edu.ua/handle/123456789/27979
Title: | Features of the Severity of Cardiovascular Remodeling and Metabolic Disorders in Hypertensive Patients with Obesity in the Presence of Two Unfavorable Genotypes of the ADIPOQ and IRS-1 Genes |
Authors: | Shalimova, Anna Psarova, Valentyna Kyrychenko, Nataliia Kochuieva, Maryna |
Keywords: | diabetes mellitus metabolic disorders obesity hypertension |
Issue Date: | 2020 |
Citation: | Features of the Severity of Cardiovascular Remodeling and Metabolic Disorders in Hypertensive Patients with Obesity in the Presence of Two Unfavorable Genotypes of the ADIPOQ and IRS-1 Genes / A. Shalimova, V. Psarova, N. Kyrychenko, M. Kochuieva // Journal of the Endocrine Society. – 2020. – Vol. 4, Abstract Supplement. – A35–A36. |
Abstract: | The results of a number of studies have shown that in ar- terial hypertension (AH), G/T and T/T genotypes of the adiponectin gene (ADIPOQ) and Gly/Arg and Arg/Arg genotypes of the insulin receptor substrate 1 gene (IRS-1) are associated with a greater severity of metabolic disorders and hemodynamic parameters compared with G/G and Gly/ Gly genotypes of these genes. The aim of the study: to evaluate the severity of cardiovas- cular remodeling and metabolic disorders in hypertensive obese patients in the simultaneous presence of two unfa- vorable genotypes of the ADIPOQ and IRS-1 genes. |
URI: | https://repo.knmu.edu.ua/handle/123456789/27979 |
Appears in Collections: | Наукові праці. Кафедра внутрішньої медицини № 1 |
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bvaa046.070.pdf | 139,29 kB | Adobe PDF | View/Open |
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