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http://repo.knmu.edu.ua/handle/123456789/27636| Title: | Correlation between the lymphocyte-monocyte ratio and cytokines in chronic inflammation in rats treated with allogeneic mesenchymal stem cells |
| Other Titles: | Кореляція між лимфоцитарно-моноцитарний співвідношенням і цитокінами при хронічному запаленні у щурів, які отримували алогенні мезенхімальні стовбурові клітини |
| Authors: | Petryk, Nataliia Shevchenko, Oleksandr |
| Keywords: | lymphocyte-monocyte rate C-reactive protein chronic inflammation mesenchymal stem cells tumor necrosis factor-α interleukin-6 |
| Issue Date: | 2020 |
| Citation: | Petryk N. D. Correlation between the lymphocyte-monocyte ratio and cytokines in chronic inflammation in rats treated with allogeneic mesenchymal stem cells / N. D. Petryk, O. M. Shevchenko // Inter collegаs. – 2020. – Vol. 7, N 3. – Р. 109–111. |
| Abstract: | The inflammation model was chronic aseptic myositis caused by an intramuscular injection of 10mg λ-carrageenan (Sigma-Aldrich GmbH). Our experimental groups of rats were treated with MSCs (the injection into the inflamed site) in the amount of 1-2 million cells once. Blood sampling was performed from 6 hours to 28 days. We calculated our results using Statistica (data analysis software) version 13. For comparison, we used one-way ANOVA, Turkey's post hoc test, where p <0.05 was considered statistically significant. In our experiment, the correlation between levels of α-TNF, IL-6, and CRP with LMR in rats was described for the first time, demonstrating the suppression of chronic inflammation through MSCs |
| URI: | https://repo.knmu.edu.ua/handle/123456789/27636 |
| Appears in Collections: | Наукові праці. Кафедра загальної та клінічної патофізіології імені Д.О. Альперна |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Correlation LMR and Cytokines edited.docx | 472,16 kB | Microsoft Word XML | View/Open |
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