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  3. Кафедра пропедевтики внутрішньої медицини № 1, основ біоетики та біобезпеки
  4. Наукові праці. Кафедра пропедевтики внутрішньої медицини № 1, основ біоетики та біобезпеки
Please use this identifier to cite or link to this item: http://repo.knmu.edu.ua/handle/123456789/2495
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dc.contributor.authorDemydenko, Ganna-
dc.contributor.authorKovalyova, Olga-
dc.contributor.authorKochubiei, Oksana-
dc.date.accessioned2012-12-14T11:52:01Z-
dc.date.available2012-12-14T11:52:01Z-
dc.date.issued2012-
dc.identifier.citationDemydenko G. Oncostatin M activity and cardiac remodeling in patients with arterial hypertension and type 2 diabetes mellitus / G. Demydenko, O. Kovalyova, O. Kochubei // Journal of Hypertension. – 2012. – Vol. 30, Supl. A, April. – P. 448–449.uk_UK
dc.identifier.urihttps://repo.knmu.edu.ua/handle/123456789/2495-
dc.description.abstractOncostatin M (OSM) is an inflammatory cytokine that belongs to the interleukin-6 (IL-6) class of cytokines. Members of this family mostly associated with cardiac hypertrophy due to activation of the common coreceptor gp130. Influence of OSM on cardiomyocytes in human is still controversial. Functional studies revealed that OSM is sufficient to induce dedifferentiation of cardiomyocytes in vitro and in vivo. OSM induces heterodimerization of gp130 with the OSM receptor β. Left ventricle (LV) remodeling is known as predictor of macrovascular outcomes in patients with arterial hypertension (AH) and type 2 diabetes mellitus (T2DM).uk_UK
dc.language.isoenuk_UK
dc.subjectcardiac remodelinguk_UK
dc.subjectarterial hypertensionuk_UK
dc.titleOncostatin M activity and cardiac remodeling in patients with arterial hypertension and type 2 diabetes mellitus.uk_UK
dc.typeArticleuk_UK
Appears in Collections:Наукові праці. Кафедра пропедевтики внутрішньої медицини № 1, основ біоетики та біобезпеки

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