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Please use this identifier to cite or link to this item: http://repo.knmu.edu.ua/handle/123456789/20308

Название: Human Red Blood Cell Properties and Sedimentation Rate: a Biomechanical Study
Авторы: Kizilova, Natalya
Batyuk, Liliya
Cherevko, Vitalina
Ключевые слова: red blood cells
electric potential
Medical diagnostics
sedimentation rate
Issue Date: 7-Sep-2018
Издатель: Springer International Publishing
Библиографическое описание: Kizilova N. Human Red Blood Cell Properties and Sedimentation Rate: a Biomechanical Study / N. Kizilova, L. Batyuk, V. Cherevko // Biomechanics in Medicine and Biology : Proceedings of the International Conference of the Polish Society of Biomechanics, Zielona Gora, Poland, September 5-7, 2018 / K. Arkusz, R. Bedzinski, T. Klekiel, S. Piszczatowski, eds. - 2019. - P. 3–22. – (Springer Series «Advances in Intelligent Systems and Computing», Vol.831). – doi.org/10.1007/978-3-319-97286-2_1.
Аннотация: Human blood is widely used for clinical diagnostics due to its easy accessibility and high sensitivity for any metabolic disorders and diseases. In the paper different mechanical and electric properties of red blood cells (RBC) useful for diagnostics are discussed. The experimental data on the erythrocyte sedimentation rate (ESR) test in its standard procedure and continuous computer assisted assessment are presented. The review of mathematical approaches for reasonable ESR estimation is given. The continuous model of blood as three phase suspension is used for numerical estimation of aggregate ability of RBC. The problem on RBC aggregation and sedimentation in a thin vertical tube is considered. A numerical solution of the formulated hyperbolic problem is obtained by the method of characteristics. Numerical computations have been carried out for a wide range of RBC parameters proper to healthy state and patients with cancer, drug and food allergy. It is shown the continuous sedimentation curves give more diagnostic information than the standard ESR value. Based on the experimental and theoretical study, a biomechanical interpretation of the ESR curves is proposed.
URI: http://repo.knmu.edu.ua/handle/123456789/20308
Appears in Collections:Наукові праці. Кафедра медичної та біологічної фізики і медичної інформатики

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