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http://repo.knmu.edu.ua/handle/123456789/1983| Title: | PPARγ, AT1R and ace gene polymorphisms in relation to hypotensive therapy effectiveness in hipertensive patients with obesity and/or type 2 diabetes mellitus |
| Authors: | Honchar, Oleksii Gryaznova, Olga |
| Keywords: | polymorphism of PPARγ AT1R and ACE genes hypotensive therapy |
| Issue Date: | 2012 |
| Publisher: | KNMU |
| Citation: | Gonchar O. PPARγ, AT1R and ace gene polymorphisms in relation to hypotensive therapy effectiveness in hipertensive patients with obesity and/or type 2 diabetes mellitus / O. Gonchar, O. Gryznova // 5th International Scientific Interdisciplinary Conference (ISIC) for medical students and young doctors, Kharkiv, April 25–26, 2012 : Abstract book. – Kharkiv, 2012. – P. 52–53. |
| Abstract: | The best sensitivity to treatment with telmisartan was shown by ProPro homozygotes, the presence of Ala-allele and C-allele of AT1R gene was associated with decreased response. HAla /AC+CC seem to be the most unfavorable combination of genes in terms of telmisartan effectiveness in patients with hypertension and DM II. In hypertensive patients with obesity the best response to treatment with ramipril was observed in patients with II genotype of ACE gene, and in DD carriers with indapamide. |
| URI: | https://repo.knmu.edu.ua/handle/123456789/1983 |
| Appears in Collections: | Наукові роботи молодих вчених. Кафедра внутрішньої медицини № 1 |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| gonchar.pdf | 281,22 kB | Adobe PDF |  View/Open |
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