The correlation between metabolic, hemodinamic, structural and functional disorders in patients with nonalcohlic fatty liver disease and arterial hypertension

Abstract

It is analyzed the factors of progression of metabolic disorders in the liver and the changes in intracardiac hemodynamics in patients with nonalcoholic fatty liver disease in combination with hypertension. The predictors of progression of metabolic disorders in the liver in case of NAFLD associated with AH are the following: ALT activity; the level of total cholesterol; VLDL; HOMA-IR index; BMI and the presence of diastolic dysfunction due to disorders of diastolic relaxation; left ventricular systolic dysfunction with a decrease of contractile ability; left ventricular remodeling that contributes to the development and progression of liver fibrosis and increases the risk of cardiovascular complications.