Pathology of the biliary tract in patients with osteoarthritis and obesity.
Date
2016-01-20
Authors
Pasiyeshvili, L.
Pasiyeshvili, N.
Karpenko, V.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
An increase in IL-6, which appears in the inflammation after 2-3 days
from the start of the disease, associated with the synthesis of acute phase proteins by
hepatocytes and the control of fibrogenesis (reduced activity). In this case, we
can say that combined OA and obesity rate has practically no effect of IL-6 for
being in clinical remission. Those, there is not an active inflammatory process
in the liver, and the resulting changes are due to the formation of liver’s steatosis
background changes of lipid and carbohydrate metabolism. At the same time,
changes in ultrasonic indicates gallbladder inflammation occurred with the
change of physical and chemical properties of bile.
Thus, the presence of obesity in patients with OA may contribute to the
formation of hepatobiliary disease that aggravate the clinical manifestations of
the disease.
Description
Keywords
Pathology of the biliary tract, obesity, osteoarthritis
Citation
Pasiyeshvili L. M. Pathology of the biliary tract in patients with osteoarthritis and obesity / L. M. Pasiyeshvili, N. M. Pasiyeshvili, V. G. Karpenko // Університетська клініка: захворювання гепатобіліарної системи з позицій поліпрофільного підходу : матеріали щорічної науково-практичної конференції з міжнародною участю, Харків, 20 січня 2016 р. / за ред. В. І. Савенков, Л. М. Пасієшвілі [та ін.]. – Харків, 2016. – С. 7–9.