The features of carbohydrate metabolism disorders in patients co-infected with HIV/HCV

Abstract

This article discussed the state of carbohydrate metabolism in HIV-infected persons, patients with chronic hepatitis C (CHC) and patients co-infected with HIV/HCV. The study of carbohydrate metabolism ofblood was performed in 107 patients, including: CHC patients — 36 with HIV — 35, co-infection with HIV/HCV — 36. In the investigated patients identified carbohydrate metabolism disorders as an increase in serum glucose, insulin, glycosylated hemoglobin, level of insulin resistance. The most significant manifestations of disorders of carbohydrate metabolism were observed in patients co-infected with HIV/HCV (t = 27.4; p < 0.001), that exceed a specified changes in patients with HCV 1.53 times (t = 17.9; p < 0.001) and HIV-infected patients (t = 12.8; p < 0.001) 2.14 times.