Behar, JoachimBonnemains, LaurentShulgin, VyacheslavOster, JulienOstras, OleksiiLakhno, Igor2023-05-082023-05-082019-01-02Noninvasive fetal electrocardiography for the detection of fetal arrhythmias / J. A. Behar, L. Bonnemains, V. Shulgin, J. Oster, O. Ostras, I. Lakhno // Prenatal Diagnosis. – 2019. – Vol. 39, No 3. – P. 178–187.https://doi.org/10.1002/pd.5412https://repo.knmu.edu.ua/handle/123456789/32020Objective: To assess whether noninvasive fetal electrocardiography (NI‐FECG) enables the diagnosis of fetal arrhythmias. Methods: A total of 500 echocardiography and NI‐FECG recordings were collected from pregnant women during a routine medical visit in this multicenter study. All the cases with fetal arrhythmias (n = 12) and a matching number of control (n = 14) were used. Two perinatal cardiologists analyzed the extracted NI‐FECG while blinded to the echocardiography. The NI‐FECG‐based diagnosis was compared with the reference fetal echocardiography diagnosis. Results: NI‐FECG and fetal echocardiography agreed on all cases (Ac = 100%) on the presence of an arrhythmia or not. However, in one case, the type of arrhythmia identified by the NI‐FECG was incorrect because of the low resolution of the extracted fetal P‐wave, which prevented resolving the mechanism (2:1 atrioventricular conduction) of the atrial tachycardia. Conclusion: It is possible to diagnose fetal arrhythmias using the NI‐FECG technique. However, this study identifies that improvement in algorithms for reconstructing the P‐wave is critical to systematically resolve the mechanisms underlying the arrhythmias. The elaboration of a NI‐FECG Holter device will offer new opportunities for fetal diagnosis and remote monitoring of problematic pregnancies because of its low‐cost, noninvasiveness, portability, and minimal setup requirements.enfetal non-invasive electrocardiographyfetal monitoringfetal arrhythmiaNoninvasive fetal electrocardiography for the detection of fetal arrhythmiasArticle