Vasylyev, D.Chernobay, LarysaVasylieva, O.Oliinyk, M.Vashuk, M.2017-09-212017-09-212017-06Clinical and genetic peculiarities of vascular manifestations of antiphospholipid syndrome (case report) / D. Vasylyev, L. Chernobay, O. Vasylieva, M. Oliinyk, M. Vashuk // Georgian Medical News. – 2017. – № 6 (267). – Р. 114–119.https://repo.knmu.edu.ua/handle/123456789/17406APS is a model of an autoimmune thrombosis that occurs against the background of a particular primary disorder. All patients of young age with unprovoked thrombosis of deep veins of lower extremities and PE are subjected to examination on APS and hereditary thrombophilias.Pathogenetic mechanisms of the development of antiphospholipid syndrome (APS) are considered in the article, which is the basis for the development of clinical manifestations and laboratory markers of APS. The modern literature data are analyzed, according to which the presence of antiphospholipid antibodies is a hypercoagulable background, and the formation of thrombi occurs under the influence of other allowing procoagulation factors. The classification of the main types of hereditary thrombophilia is given, which is the primary disorder, against the background of which an autoimmune thrombosis APS develops.enantiphospholipid syndromemarkersthrombogenesisdiagnosticsArticle