Browsing by Subject "osteomyelitis"
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Item Immunological Aspects of Carbohydrate and Lipid Metabolism in Patients with Periprosthetic Infection and Osteomyelitis(2020-04) Kravchun, Pavlo; Korzh, Mykola; Dunaieva, Inna; Leontieva, Frida; Gusakov, Igor; Krapivko, Svitlana; Dielievska, ValentynaIntroduction Treatment of patients with periprosthetic in- fection and osteomyelitis is rather challenging. The objective of the research was to evaluate the metabolism of carbohydrates and lipids and immunological profile in patients with periprosthetic infection and osteomyelitis. Material and methods A study on carbohydrate and lipid metabolism and immunological examination of patients with periprosthetic infection after knee and hip joint endo- prosthetics (n = 16) and osteomyelitis (n = 20) was conducted. Results The patients with periprosthetic infection were characterized by anemia, impaired glucose tolerance, predisposition to enhanced atherogenesis, autoimmune granulocytotoxic antibodies and sensitization to synovial membrane and Staphylococcus aureus. The patients with osteomyelitis showed decrease of production of the leukocyte migration inhibition factor (LIF), both nonspecific and to the antigens of cartilage tissue, as well as sensitization to Streptococcus and E. coli. In the patients studied glucose metabolism disturbances have been associated with the presence of autoimmune lymphocytotoxic antibodies, reduced production of LIF, both nonspecific and to the antigens of synovial membrane. Atherogenesis was associated with increased circulating immune complexes, autoim- mune lymphocytotoxic and granulocytotoxic antibodies,decreased LIF and sensitization to the antigens of connective tissue, Streptococcus and Proteus. Anemia was associated with increased autoimmune lymphocytotoxic antibodies, delayed type sensitization to bone and cartilage tissue, to Staphylococcus and sensitization by accelerated type to E. coli and Proteus. Conclusions Physicians should analyze immunological data while treating and monitoring the patients with connective tissue infections and disturbances of glucose and cholesterine metabolism.Item Immunological Aspects of Carbohydrate and Lipid Metabolism in Patients with Periprosthetic Infection and Osteomyelitis(2020-04) Kravchun, Pavlo H.; Korzh, Mykola; Dunaieva, Inna; Leontieva, Frida; Gusakov, Igor; Krapivko, Svitlana; Dielievska, ValentynaIntroduction Treatment of patients with periprosthetic in- fection and osteomyelitis is rather challenging. The objective of the research was to evaluate the metabolism of carbohydrates and lipids and immunological profile in patients with periprosthetic infection and osteomyelitis. Material and methods A study on carbohydrate and lipid metabolism and immunological examination of patients with periprosthetic infection after knee and hip joint endo- prosthetics (n = 16) and osteomyelitis (n = 20) was conducted. Results The patients with periprosthetic infection were characterized by anemia, impaired glucose tolerance, predisposition to enhanced atherogenesis, autoimmune granulocytotoxic antibodies and sensitization to synovial membrane and Staphylococcus aureus. The patients with osteomyelitis showed decrease of production of the leukocyte migration inhibition factor (LIF), both nonspecific and to the antigens of cartilage tissue, as well as sensitization to Streptococcus and E. coli. In the patients studied glucose metabolism disturbances have been associated with the presence of autoimmune lymphocytotoxic antibodies, reduced production of LIF, both nonspecific and to the antigens of synovial membrane. Atherogenesis was associated with increased circulating immune complexes, autoim- mune lymphocytotoxic and granulocytotoxic antibodies,decreased LIF and sensitization to the antigens of connective tissue, Streptococcus and Proteus. Anemia was associated with increased autoimmune lymphocytotoxic antibodies, delayed type sensitization to bone and cartilage tissue, to Staphylococcus and sensitization by accelerated type to E. coli and Proteus. Conclusions Physicians should analyze immunological data while treating and monitoring the patients with connective tissue infections and disturbances of glucose and cholesterine metabolism.Item Pediatrics acute hematogenous osteomyelits(2019-04-13) Thuraya, Ismail Al-Bhaisi; Vivcharuk, Victoria; Pashchenko, Konstantin; Shtyker, StanislavOsteomyelitis is a bacterial inflammation of bones, it mostly affects long bones. It occurs when the bacterium travels from its original site to the bone. It is more common in children because there is higher blood circulation in bones which provides necessary nutrition for their growth.Item Результаты комплексного лечения больных хроническим токсическим остеомиелитом челюстей(2015) Рузін, Геннадій Пінхусович; Рузин, Геннадий Пинхусович; Ruzin, G.; Ткаченко, Оксана Валеріївна; Ткаченко, Оксана Валерьевна; Tkachenko, O.