Browsing by Author "Bondar, O."
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Item Acute appendicitis on background of antiviral therapy of chronic hepatitis C(Kharkiv National Medical University, 2013-05-16) Lisanec, K.; Kopylov, N.; Bondar, O.Item Comparative evaluation of liver sonoelastography and fibrotest in patients with chronic hepatitis C.(2015-03-30) Bondar, O.; Solomennik, A.; Sokhan, A.; Ancyferova, N.; Blagko, V.; Deonega, A.Item Diagnostic value of gamma-glutamyl transpeptidase level in patients with chronic hepatitis C(2015-05) Ostropolets, A.; Solomennyk, A.; Bondar, O.; Mohylenets, Olena; Iurko, Kateryna; Antsyferova, NataliaItem Effectiveness of the drug phosphogliv in patients with chronic hepatitis C(2014-03) Kozko, Volodymyr; Solomennik, G.; Bondar, O.; Mohylenets, Olena; Merkulova, Nina; Vinokurova, O.; Iurko, Kateryna; Minakova, S.Item Frequency of hematologic disorders in patients with chronic hepatitis C receiving antiviral therapy(2014-03) Bondar, O.; Kozko, Volodymyr; Solomennik, A.; Sokhan, A.Item Hematologikal disorders in patients with chronic hepatitis C during antiviral therapy(2015-03-30) Kozko, Volodymyr; Bondar, O.; Solomennik, A.; Sokhan, A.; Ancyferova, N.; Penkov, D.; Katelevskaya, V.Item Identification of apolipoprotein A1 in the blood serum of patients with chronic hepatitis C(2014) Minakova, S.; Solomennik, A.; Bondar, O.; Mogilenets, O.; Yurko, K.; Vinokurova, O.Item Informativeness of structural and biochemical changes inthe muscle tissue of myocardium in the early postmortem period(2021-11) Cherkashina, Lidiya; Bondar, O.; Patalakha, O.; Shkliar, Anton; Sukhonosov, Roman; Toryanik, I.; Demikhova, Nadiia; Barchan, GannaAt the present stage in the development of forensic medicine scientists have suggested different differential-diagnostic criteria for determining the prescription of death coming (PDC), which give positive results and help in coping with a number of problems that have not been solved yet. But the overwhelming majority of the suggested modern methods of investigation cause difficulties in their introduction into everyday practice, most frequently due to problems with material and technical support for forensic examinations (FE).The modern practice and tactics of forensic diagnosis require scientific substantiation of informative diagnostic criteria for assessing PDC, first of all within the early postmortem period (PMP). The above substantiationis caused by a need for an increased accuracy and can be realized by means of objectification of structural and biochemical changes in different organs and tissues of the human organism. In particular, the interest of scientists and practitioners in FE is attracted by structural and biochemical changes in the muscle tissue (MT) of different morphological types. The known methods for diagnosing PDC are based on registration of the existing postmortem rigidity of the body, appearance of cadaveric lividity and some other diagnostic signs. Nevertheless the use of the above criteria for diagnosing PDC in the majority of cases is not able to form forensic conclusions about PDC with a high reliability and accuracy. At the same time, time-dependent regularities in changes of biochemical (BCM) and biophysical markers (BPM) of the state of MT within the first hours after the coming of death remain insufficiently studied.Item Noninvasive diagnostics of hepatic steatosis in patients with chronic hepatitis C(2015-03-30) Kozko, Volodymyr; Solomennik, G.; Bondar, O.; Mohylenets, Olena; Iurko, Kateryna; Merkulova, Nina; Vinokurova, O.; Ostropolets, G.Item Predicting the effectiveness of antiviral therapy in patients with chronic hepatitis c genotype 1(2014-03) Bondar, O.; Kozko, Volodymyr; Solomennik, A.; Sokhan, A.Item Quality of life in patients with chronic hepatitis C(Kharkiv National Medical University, 2013-05-16) Omelchenko, A.; Khaziev, A.; Bondar, O.Item Some features of the eye test in persons who are systematically involved in sports(2019-05-15) Kyrychenko, Michael; Marakushyn, Dmytro; Shenher, S.; Dunaieva, Olha; Bondar, O.The paper presents the results of an eye test in athletes of various types of sports specialization and qualification. The study was conducted in 3 stages: the training period, the competition period and the recovery period. Three types of reactions were identified: normotonic, vagotonic, and sympathic-kinetic. It was noted a moderate impact of psycho-emotional factors on the nature of the determined reactions of autonomic inhibition of the heart. Based on the data obtained, the following conclusions were made: 1) athletes may experience various deviations from the normal type of reaction to the ocular test; 2) the nature of the reactions of the heart to the eye test depends on the nervous and humoral effects on the heart affecting the functional state of this organ in the process of sports activity.Item The analysis of medical workers contamination with hepatitis c according to the Kharkiv regional hepatology center(2014) Movsesian, A.; Bezyazichna, N.; Solomenic, N.; Bondar, O.; Korzh, E.; Vaniyants, A.Item The location of extrahepatic manifestations in the clinical picture of chronic HCV-infection(2015-03-30) Ancyferova, N.; Solomennyk, A.; Kopiychenko, Yaroslava; Bondar, O.; Kuznetsova, Anastasiia; Pen`kov, D.Item The role of polymorphism ASP299GLY of the gene TLR 4 in patients co-infected with HIV/HCV(Tbilisi State Medical University, 2018-07) Yurko, K.; Kozko, Volodymyr; Solomennik, A.; Bondar, O.; Sokhan, A.; Gavrylov, AnatoliyFor the first time it was conducted complex research of metabolic disorders in patients co-infected with HIV/HCV and was shown that they are characterized by disturbances of mineral, lipid and carbohydrate metabolism types. It was established significantly higher values of indicators of mineral, lipid and carbohydrate metabolism types in patients co-infected with HIV/HCV compared with patients with chronic hepatitis C and HIV-infected persons. In patients co-infected HIV/HCV appears significantly more frequent the polymorphism Asp299Gly of the gene TLR4 (χ2 = 4,5; p<0,05) when compared with healthy donors, which plays a significant role in the development of metabolic disorders, such correlation is confirmed by those relationships: a strong direct relationship between the polymorphism Asp299Gly of TLR4 gene and the content of insulin (r = 0,66; p<0,001), insulin resistance (r=0,66; p<0,001), the absolute number of CD45+ of T-lymphocytes (r=0 45; p<0,001); a moderate direct relationship with the content of TNF-α (r=0,32; p<0,05), CRP (r=0,34; p<0,05), the absolute number of CD3+ of T-lymphocytes (r=0,34; p<0,05), the content of triglyceride (r=0,39; p<0,02), moderate inverse relationship with the zinc content (r = -0,34; p<0,05 ), the relative number of CD4 +,% (r = -0,32; p<0,05). The system of monitoring of metabolic disorders in patients co-infected with HIV/HCV based on the definition of polymorphism Asp299Gly gene TLR4, the presence of which indicates a high risk of metabolic disturbances (OR=23,3; p<0,05) and requires further investigation, namely the definition of an index of insulin resistance, insulin levels, TNF-α, C-reactive protein, zinc and triglyceride levels in dynamics at intervals of 6 months that allow for timely diagnosis and correction of metabolic disorders.