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\rsid16585716\rsid16589413\rsid16591450\rsid16597367\rsid16600738\rsid16605052\rsid16610028\rsid16652024\rsid16652344\rsid16652870\rsid16655297\rsid16658115\rsid16658410\rsid16658816\rsid16660021\rsid16670253\rsid16676167\rsid16678211\rsid16713685
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rdml}}\paperw11906\paperh16838\margl1701\margr850\margt1134\margb1134\gutter0\ltrsect 
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\noxlattoyen\expshrtn\noultrlspc\dntblnsbdb\nospaceforul\formshade\horzdoc\dgmargin\dghspace180\dgvspace180\dghorigin1701\dgvorigin1134\dghshow1\dgvshow1
\jexpand\viewkind1\viewscale100\pgbrdrhead\pgbrdrfoot\splytwnine\ftnlytwnine\htmautsp\nolnhtadjtbl\useltbaln\alntblind\lytcalctblwd\lyttblrtgr\lnbrkrule\nobrkwrptbl\snaptogridincell\allowfieldendsel\wrppunct
\asianbrkrule\rsidroot8744913\newtblstyruls\nogrowautofit\utinl \fet0{\*\wgrffmtfilter 2450}\ilfomacatclnup0\ltrpar \sectd \ltrsect\linex0\headery708\footery708\colsx708\endnhere\sectlinegrid360\sectdefaultcl\sectrsid12588861\sftnbj {\*\pnseclvl1
\pnucrm\pnstart1\pnindent720\pnhang {\pntxta .}}{\*\pnseclvl2\pnucltr\pnstart1\pnindent720\pnhang {\pntxta .}}{\*\pnseclvl3\pndec\pnstart1\pnindent720\pnhang {\pntxta .}}{\*\pnseclvl4\pnlcltr\pnstart1\pnindent720\pnhang {\pntxta )}}{\*\pnseclvl5
\pndec\pnstart1\pnindent720\pnhang {\pntxtb (}{\pntxta )}}{\*\pnseclvl6\pnlcltr\pnstart1\pnindent720\pnhang {\pntxtb (}{\pntxta )}}{\*\pnseclvl7\pnlcrm\pnstart1\pnindent720\pnhang {\pntxtb (}{\pntxta )}}{\*\pnseclvl8\pnlcltr\pnstart1\pnindent720\pnhang 
{\pntxtb (}{\pntxta )}}{\*\pnseclvl9\pnlcrm\pnstart1\pnindent720\pnhang {\pntxtb (}{\pntxta )}}\pard\plain \ltrpar\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12342795 \rtlch\fcs1 \af0\afs22\alang1025 
\ltrch\fcs0 \fs22\lang1049\langfe1033\loch\af37\hich\af37\dbch\af37\cgrid\langnp1049\langfenp1033 {\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \b\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 
ASSOCIATION BETWEEN ADIPOCYTOKINES AND INSULIN RESISTANCE IN PATIENTS WITH METABOLIC DISORDERS}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \b\f0\fs24\lang1033\langfe1033\langnp1033\insrsid8744913\charrsid12342795 
\par }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid10691534\charrsid12342795 O.V. Goptsii}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 , 
\par }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1033\langnp1033\insrsid8744913\charrsid16537246 \hich\af0\dbch\af37\loch\f0 Kharkiv National Medical University}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1033\langnp1033\insrsid16537246\charrsid16537246 \hich\af0\dbch\af37\loch\f0 , \hich\af0\dbch\af37\loch\f0 Kharkiv,\hich\af0\dbch\af37\loch\f0  \hich\af0\dbch\af37\loch\f0 Ukraine}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1033\langnp1033\insrsid16537246 .}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\lang1033\langfe1033\langnp1033\insrsid8744913\charrsid16537246 
\par }\pard \ltrpar\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12342795 {\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid10691534\charrsid16537246 
\par }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \b\f0\fs24\lang2057\langfe1033\langnp2057\insrsid10691534\charrsid16537246 \hich\af0\dbch\af37\loch\f0 The purpose}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\lang2057\langfe1033\langnp2057\insrsid10691534\charrsid16537246 .}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid16537246 Study of activity of TNF-}{\rtlch\fcs1 \af189\afs24 
\ltrch\fcs0 \f189\fs24\cf1\lang1049\langfe1049\langfenp1049\insrsid10691534\charrsid16537246 \'e1}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid16537246 
 and leptin depending on the presence of insulin}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 
 resistance (IR) in patients with arterial hypertension with concomitant obesity. }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid10691534\charrsid12342795 
\par }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \b\f0\fs24\lang1033\langfe1033\langnp1033\insrsid10691534\charrsid12342795 \hich\af0\dbch\af37\loch\f0 Materials and Methods}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\lang1033\langfe1033\langnp1033\insrsid10691534\charrsid12342795 \hich\af0\dbch\af37\loch\f0 . }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 
123 patients suffering from arterial hypertension with concomitant obesity were investigated. The levels of }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid10691534\charrsid12342795 TNF-}{\rtlch\fcs1 
\af189\afs24 \ltrch\fcs0 \f189\fs24\cf1\lang1049\langfe1049\langfenp1049\insrsid10691534\charrsid12342795 \'e1}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 
, leptin and insulin were identified by means of immunoenzyme method. The Insulin Resistance Index (HOMA index) was calculated using the formula: HOMA index = fasting blood glucose (mmol/l) x fasting blood insulin (}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\lang1033\langfe1033\langnp1033\insrsid12342795\charrsid12342795 \hich\af0\dbch\af37\loch\f0 mkgU/ml}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 
) / 22.5. HOMA Index > 2.77 }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 cu}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795  is associated with the presence of IR. }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid10691534\charrsid12342795 
\par }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \b\f0\fs24\lang2057\langfe1033\langnp2057\insrsid10691534\charrsid12342795 \hich\af0\dbch\af37\loch\f0 Results}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\lang2057\langfe1033\langnp2057\insrsid10691534\charrsid12342795 .\hich\af0\dbch\af37\loch\f0  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 
All the patients were divided into two groups: the 1st group consisted of 80 patients without IR (insulin level 7.60\'b10.35 }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\lang1033\langfe1033\langnp1033\insrsid10691534\charrsid12342795 
\hich\af0\dbch\af37\loch\f0 mkgU/ml}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 , HOMA index 1.47\'b10.06 }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid10691534\charrsid12342795 cu}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 
); the 2nd group consisted of 43 patients with IR (insulin level 31.35\'b12.51 }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\lang1033\langfe1033\langnp1033\insrsid10691534\charrsid12342795 \hich\af0\dbch\af37\loch\f0 mkgU/ml}{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 , HOMA index 7.22\'b10.68 }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid10691534\charrsid12342795 
cu}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 ). It was established that the indices of blood pressure}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid10691534\charrsid12342795  (BP)}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 
 in the patients with IR were higher (S}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid10691534\charrsid12342795 ystolic }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 BP 182.44\'b12.50 mmHg, D}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 iastolic }{
\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 BP 104.21\'b11.17 mmHg) in comparison to hypertensive patients without IR (}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 Systolic }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 BP 167.75\'b11.66 mmHg, }{
\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 Diastolic }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 BP 100.01\'b10.87 mmHg). The levels of }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 
TNF-}{\rtlch\fcs1 \af189\afs24 \ltrch\fcs0 \f189\fs24\cf1\lang1049\langfe1049\langfenp1049\insrsid12342795\charrsid12342795 \'e1}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 
 }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 and leptin increased evidently in hypertensive patients with IR (}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 TNF-}{\rtlch\fcs1 \af189\afs24 \ltrch\fcs0 \f189\fs24\cf1\lang1049\langfe1049\langfenp1049\insrsid12342795\charrsid12342795 \'e1}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 10.38\'b10.66 pg/m}{\rtlch\fcs1 
\af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 l}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 , leptin 13.24
\'b10.81 ng/m}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 l}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 , in female patients 13.74\'b10.99 ng/m}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 
l}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 , in male patients 12.38\'b11.40 ng/m}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 l}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 
) in comparison to the patients without IR (}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 TNF-}{\rtlch\fcs1 \af189\afs24 \ltrch\fcs0 
\f189\fs24\cf1\lang1049\langfe1049\langfenp1049\insrsid12342795\charrsid12342795 \'e1}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 5.95\'b10.29 pg/m}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 l, leptin 9.7}{
\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 \'b10.86 ng/m}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 l}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 , in female patients 11.41\'b1
1.32 ng/m}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 l}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 , in male patients 7.07\'b10.53 ng/m}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 l}{
\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 ), }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 p
}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795  <0.005. }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 
\par }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 In correlation analysis in the group of the patients with IR a positive }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 cor}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 
relation between the level of insulin and }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 TNF-}{\rtlch\fcs1 \af189\afs24 \ltrch\fcs0 
\f189\fs24\cf1\lang1049\langfe1049\langfenp1049\insrsid12342795\charrsid12342795 \'e1}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 (R=0.46; }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 p}{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 <0.004), level of leptin (R=0.32; }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 p}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 <0.03); HOMA index and }{\rtlch\fcs1 
\af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 TNF-}{\rtlch\fcs1 \af189\afs24 \ltrch\fcs0 \f189\fs24\cf1\lang1049\langfe1049\langfenp1049\insrsid12342795\charrsid12342795 \'e1}{\rtlch\fcs1 
\af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 (R=0.44; }{
\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 p}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 
<0.005), level of leptin (R=0.33; }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 p}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 <0.03); level of leptin and }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 TNF-}{
\rtlch\fcs1 \af189\afs24 \ltrch\fcs0 \f189\fs24\cf1\lang1049\langfe1049\langfenp1049\insrsid12342795\charrsid12342795 \'e1}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795  }{
\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 (R=0.57; }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 p}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 <0.00001) was established. }{
\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid10691534\charrsid12342795 
\par }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 Conclusion:}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid16537246  }{
\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 The activity of }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 TNF-}{\rtlch\fcs1 \af189\afs24 \ltrch\fcs0 \f189\fs24\cf1\lang1049\langfe1049\langfenp1049\insrsid12342795\charrsid12342795 \'e1}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 
and leptin increase evidently in hypertensive patients with IR in comparison to the group of patients without IR (}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 p}{
\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 <0.001). Direct correlation dependence in the group of the patients with IR between the levels of }{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid12342795\charrsid12342795 TNF-}{\rtlch\fcs1 \af189\afs24 \ltrch\fcs0 \f189\fs24\cf1\lang1049\langfe1049\langfenp1049\insrsid12342795\charrsid12342795 \'e1}{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \f0\fs24\cf1\lang1033\langfe1049\langnp1033\langfenp1049\insrsid8744913\charrsid12342795 , leptin and Insulin Resistance Index was established.}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\f0\fs24\lang1033\langfe1033\langnp1033\insrsid8744913\charrsid12342795 
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