Abstract

CT-stereotactic biopsy of deep localized brain neoplasms
Speaker: Vladimir Piatykop
Author: Piatykop V., Kutoviy I., Naboychenko A.
Affiliation: Neurosurgical Dept, Kharkov National Medical University, Kharkov, Ukraine
Session: E-Posters
Date: Thursday - October 25, 2012 08:30-18:30
Location: Exhibition Area
Topic: Functional neurosurgery
Our aim is to optimize the available minimally invasive highly accurate method of CT-stereotactic biopsy (?TSB) of deep localized brain neoplasms (DLBN) with the possibility of intraoperative CT imaging at all stages.
Methods: CTSB was performed at 63 DLBN cases during 2000-2010yy. Women - 35, men - 28. Age 17 to 65 years. Procedure took place in cases not less than 40 points of Karnofsky. Diameter of neoplasms was from 20 to 60mm. CTSB was performed using frameless stereotactic devises of Kandel's design under the control of intraoperative spiral CT. Biopsy was performed with spiral and vacuum biopsy-needles. During procedure contrast media was used to determine the target area.
Results: Positive results were obtained at 61 (97%) patient, in 2 (3%) cases paratumorose necrosis was found. Histological verification: 34 (56%) - gliomas, 15 (25%) - malignant lymphomas, 4 (6%) - meningiomas, 8 (13%) - inflammatory process. At 5 (7.9%) patients intraoperative complications were faced in the form of intracerebral hemorrhage. Haemostatic therapy and emergency drainage of hematoma allowed to avoid pathological progression in all cases. No deaths occurred. The main advantage of this method is that all stages are carried out directly under CT-control and a neurosurgeon can take emergency measures if necessary.
Conclusions: CTSB is an effective method to determine the further treatment strategy for patients with BLBN. It enhances greatly the accuracy of aiming areas with different density and helps to control possible iatrogenic complications. Contrast allows to choose the most appropriate sites for CTSB of DLBN.