Early echocardiographic`s markers of chronic lung heart of children with a new form of bronchopulmonary dysplasia

Abstract

A total of 140 patients with a new form of bronchopulmonary dysplasia (study group) and 43 children born prematurely, had respiratory disorders, but is not formed bronchopulmonary dysplasia (comparison group). Age surveyed - 1- 36 months corrected age. The study was conducted on the basis of the Regional сentre of diagnosis and treatment of bronchopulmonary dysplasia in children, Regional children's hospital. The aim of the study was to improve the early diagnosis of chronic pulmonary heart disease in children with a new form of bronchopulmonary dysplasia by identifying marker role in end-diastolic diameter of the right ventricle, the thickness of the wall of the right ventricle and the mean pulmonary artery pressure. The study found that when comparing the end - diastolic diameter of the right ventricle in children of the main group was significantly higher than in the comparison group (p<0,01). In 67 (47,9±1,9%) patients of the main group identified indicators of end-diastolic diameter of the right ventricle in excess of 90 percentile. In the control group the diameter of the right ventricle does not exceed the 75 percentile (p<0,001). The thickness of the free wall of the right ventricle than 90 percentile in 27 (13,1±2,3%) children of the main group. The children of the comparison group thickness free wall of the right ventricle does not exceed the 90th percentile (p<0,001). A characteristic feature of children with a new form of bronchopulmonary dysplasia was dilatation of the right ventricle (KW (n = 183) = 17,3; rank- 4,1; p<0,0001), against the backdrop of a lack of compensatory hypertrophy of the right ventricular wall to increase the pressure in a small circulation (r=0,165; p>0.05). The correlation between end-diastolic diameter of the right ventricle and the mean pressure in the pulmonary artery (r=0,413; p<0.05). The higher the pressure in the pulmonary artery, the diameter of the right ventricle was no longer. However, reliable correlative relationship between indicators of end-diastolic diameter of the right ventricle and the thickness of the free wall of the right ventricle were found (r=0,165; p>0,05), indicating that the lack of compensatory hypertrophy of the right ventricular wall to increase the pressure in the pulmonary circulation. In children with a new form of bronchopulmonary dysplasia occurred inadequate compensatory hypertrophy of the right ventricular wall to increase the pressure in the pulmonary circulation, which is confirmed by the lack of reliable correlative connection between the end-diastolic diameter of the right ventricle and the thickness of the free wall of the right ventricle (r=0,165; p>0,05). Early markers of chronic pulmonary heart formation in children with a new form of bronchopulmonary dysplasia consider preservation of right ventricular dilatation (90 percentile) (λ Wilkes=0,885; F SUP 6,14; p = 0,019), against the backdrop of persistent pulmonary hypertension (λ = 0,891 Wilkes; F SUP 5,9; p = 0,021).